Clinical updates, teaching notes, and editorial context.
A compact update layer for evidence shifts, practical clinical learning, and changes to the reference library. Articles are organised for fast scanning before deeper study.
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- 25 June 2026
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4 articles tagged pharmacology
Local Anaesthetic Systemic Toxicity (LAST): Management Protocol
A life-saving guide to LAST. Immediate recognition, the Lipid Rescue protocol, and safe dosage calculations for the orthopaedic surgeon.
Orthovellum Team
anaesthesia / emergency
The 2025 Antibiotic Prophylaxis Guidelines for Open Fractures
A detailed review of the paradigm shift in open fracture antibiotic protocols. Evidence-based guidelines on duration, agent choice, and the move away from aminoglycosides.
Orthovellum Team
open-fractures / antibiotics
Osteoporosis Management for the Orthopaedic Surgeon: Closing the Care Gap
We fix the fracture, but do we fix the underlying cause? A comprehensive guide to diagnosing and managing osteoporosis, preventing the 'cascade of fractures', and establishing a Fracture Liaison Service.
Orthovellum Team
bone-health / dexa
Tranexamic Acid (TXA) in Orthopaedics: The Evidence-Based Guide
A comprehensive review of Tranexamic Acid. Topical vs IV, dosing protocols, safety in high-risk patients, and its role across trauma, arthroplasty, and spine surgery.
Orthovellum Team
txa / blood-loss