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Adult Reconstruction
intermediate
X-Type

THA Periprosthetic Joint Infection - PJI and MSIS Criteria

THA Complications

A 72-year-old man presents with 6 weeks of progressive left hip pain 2 years after THA for osteoarthritis. He reports no fever but has noted intermittent night sweats. On examination, the wound is healed but the hip is warm. Blood tests show ESR 48 mm/hr and CRP 35 mg/L. Hip aspiration yields 8,500 white blood cells per microlitre with 92% polymorphonuclear cells. Cultures are pending. Regarding periprosthetic joint infection (PJI) diagnosis:

Mark each as TRUE or FALSE

A

The 2018 ICM (International Consensus Meeting) criteria for PJI include major criteria (two positive...

B

Synovial fluid thresholds for chronic PJI (greater than 90 days from surgery) are WBC greater than 3...

C

Serum CRP is the most specific test for PJI; a normal CRP definitively rules out infection; alpha-de...

D

Alpha-defensin is an antimicrobial peptide released by neutrophils in response to pathogens; the lat...

E

This patient meets criteria for PJI based on elevated ESR (greater than 30), elevated CRP (greater t...

Answer the questions to see explanations

Click T (True) or F (False) for each option