TKA Complications
A 68-year-old man with type 2 diabetes presents with 4 weeks of increasing right knee pain, swelling, and warmth 18 months after cemented posterior-stabilized TKA. He has low-grade fevers (37.8C) and the knee is erythematous with an effusion. ESR is 65mm/hr, CRP is 48mg/L. Aspiration yields turbid fluid with WBC 42,000 cells/microL and 92% PMNs. Cultures are pending. Regarding the diagnosis of periprosthetic joint infection:
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The 2018 ICM/MSIS criteria define PJI by major criteria (two positive cultures of same organism OR s...
Alpha-defensin has sensitivity of 97-99% and specificity of 96-99% for PJI; it is not affected by an...
PJI can be reliably excluded if CRP is normal; ESR has no role in PJI diagnosis; synovial fluid cult...
Common causative organisms in TKA PJI include Staphylococcus aureus (most common), coagulase-negativ...
PJI is classified by timing: early (less than 3 months), delayed (3-12 months), and late (greater th...
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Click T (True) or F (False) for each option