Bone Biology
A 45-year-old man requires bone grafting for a tibial nonunion. The surgeon discusses various graft options including autograft from the iliac crest, allograft bone, demineralized bone matrix (DBM), and synthetic bone graft substitutes. The patient asks about the advantages and disadvantages of each option. Regarding bone grafts and substitutes:
Mark each as TRUE or FALSE
Bone graft properties include osteogenesis (living cells that form new bone), osteoinduction (recrui...
Autograft sources include iliac crest (most common, highest yield), distal femur, proximal tibia, an...
Allograft is osteogenic because it contains living cells; fresh-frozen allograft has higher disease ...
Allograft is osteoconductive and weakly osteoinductive (if processed to retain BMPs); fresh-frozen a...
Bone morphogenetic proteins (BMPs) are osteoinductive growth factors; rhBMP-2 and rhBMP-7 are FDA ap...
Answer the questions to see explanations
Click T (True) or F (False) for each option