Biomaterials
A 45-year-old man requires bone grafting for a tibial nonunion. The surgeon discusses options including autograft from the iliac crest, allograft bone, and various synthetic bone graft substitutes. The patient is concerned about donor site morbidity and asks about the properties of different graft materials. Regarding bone grafts and substitutes:
Mark each as TRUE or FALSE
Bone grafts have three key properties: osteoconduction (scaffold for bone ingrowth), osteoinduction ...
Allografts (cadaveric bone) are osteoconductive and weakly osteoinductive (processing reduces growth...
Autograft has no donor site morbidity; allografts contain living cells; ceramic bone substitutes are...
Ceramic bone substitutes (calcium phosphate - hydroxyapatite, tricalcium phosphate) are osteoconduct...
Bone morphogenetic proteins (BMPs, especially BMP-2 and BMP-7) are potent osteoinductive agents that...
Answer the questions to see explanations
Click T (True) or F (False) for each option