Bone Biology
A 45-year-old man has an atrophic non-union of a tibial shaft fracture 8 months after intramedullary nailing. There is a 3cm bone defect with poor surrounding vascularity. The surgeon is planning revision surgery and discusses bone grafting options with the registrar. Regarding the biology of bone grafting:
Mark each as TRUE or FALSE
Bone grafts work through three mechanisms: osteogenesis (living cells within the graft that directly...
Autologous cancellous bone graft (typically from iliac crest) is the gold standard; it provides oste...
Allografts provide osteogenesis since they contain living cells; autografts only provide osteoconduc...
Allografts (processed cadaveric bone) provide osteoconduction and variable osteoinduction but NO ost...
Synthetic bone substitutes (calcium phosphate, hydroxyapatite, tricalcium phosphate) provide osteoco...
Answer the questions to see explanations
Click T (True) or F (False) for each option