Bone Biology
A medical student is preparing for an orthopaedic basic science viva. The examiner asks about the cellular and molecular basis of bone remodeling, including the key regulatory pathways, the sequence of events in the remodeling cycle, and how therapeutic agents target these processes. Regarding bone remodeling:
Mark each as TRUE or FALSE
Bone remodeling is a continuous, lifelong process that replaces approximately 10% of adult skeletal ...
Osteoclasts are multinucleated cells derived from hematopoietic monocyte-macrophage lineage; they re...
Osteoclasts are derived from mesenchymal stem cells; osteoblasts are derived from hematopoietic cell...
Osteoblasts are derived from mesenchymal stem cells; they synthesize type I collagen and osteoid, re...
Therapeutic agents target the remodeling pathway: bisphosphonates inhibit osteoclast function (farne...
Answer the questions to see explanations
Click T (True) or F (False) for each option