Bone Biology
A 45-year-old marathon runner presents with right tibial stress fracture. She reports a recent significant increase in training volume. Her bone density scan is normal. The orthopaedic surgeon discusses the principles of bone adaptation with her, explaining how bone responds to mechanical loading and why sudden increases in load can exceed the bone's ability to adapt. Regarding bone remodeling and Wolff's Law:
Mark each as TRUE or FALSE
Wolff's Law states that bone adapts its structure to the mechanical loads placed upon it; increased ...
Bone remodeling occurs through Basic Multicellular Units (BMUs) which couple osteoclast resorption w...
Wolff's Law states bone structure is independent of mechanical loading; decreased loading increases ...
Mechanotransduction (conversion of mechanical stimuli to cellular response) involves osteocytes as t...
Clinical applications include understanding stress fractures (bone resorption exceeds formation with...
Answer the questions to see explanations
Click T (True) or F (False) for each option