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Basic Science
intermediate
X-Type

Calcium Phosphate Cements

Biomaterials

A 55-year-old female sustains a Schatzker Type II lateral tibial plateau fracture with 8mm articular depression after a fall. You plan ORIF with plate fixation and need to fill the metaphyseal void created when the depressed articular fragment is elevated. The patient asks about bone graft options. You discuss calcium phosphate cement as a synthetic bone void filler that can provide structural support and be replaced by bone over time, without the morbidity of autograft harvest. Regarding calcium phosphate cements:

Mark each as TRUE or FALSE

A

Calcium phosphate cements are synthetic bone void fillers composed primarily of hydroxyapatite (Ca10...

B

Calcium phosphate cements set through an isothermic chemical reaction (minimal heat generation 2-5°C...

C

Calcium phosphate cements have high compressive strength (20-50 MPa) comparable to cancellous bone (...

D

Calcium phosphate cements are both osteoconductive and osteoinductive, actively recruiting mesenchym...

E

Calcium phosphate cements can be safely used in infected bone defects because their antibacterial pr...

Answer the questions to see explanations

Click T (True) or F (False) for each option