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Basic Science
intermediate
X-Type

Articular Cartilage Biology

Musculoskeletal Biology

A 28-year-old athlete has an MRI showing a focal full-thickness cartilage defect in the medial femoral condyle. The surgeon discusses the limited healing capacity of cartilage and treatment options including microfracture, osteochondral grafting, and cell-based therapies. Regarding articular cartilage biology:

Mark each as TRUE or FALSE

A

Articular cartilage is composed of water (65-80%), collagen (10-20% wet weight, primarily type II), ...

B

The cartilage zones from superficial to deep are: superficial (tangential collagen, flattened chondr...

C

Articular cartilage has an excellent blood supply; it heals readily after injury through vascular in...

D

Proteoglycans (primarily aggrecan) consist of a core protein with attached glycosaminoglycan chains ...

E

Cartilage is aneural, avascular, and alymphatic, receiving nutrition via diffusion from synovial flu...

Answer the questions to see explanations

Click T (True) or F (False) for each option