Inflammatory Cytokines
A researcher is studying the role of inflammatory cytokines in fracture healing and is particularly interested in interleukin-6 (IL-6). The team is investigating how IL-6 levels change during the healing process and potential therapeutic implications for enhancing bone repair. Regarding IL-6 in bone biology:
Mark each as TRUE or FALSE
IL-6 is a pleiotropic cytokine produced by osteoblasts, macrophages, and T-cells; it signals through...
During fracture healing, IL-6 peaks early (within 24-48 hours) as part of the inflammatory response ...
IL-6 is only produced by osteoclasts; it has no role in fracture healing; levels remain constant dur...
IL-6 has dual effects on bone: it can stimulate bone formation through osteoblast activation but als...
Clinical implications include: anti-IL-6 therapies (tocilizumab for RA) may theoretically affect fra...
Answer the questions to see explanations
Click T (True) or F (False) for each option