Tissue Repair
A 55-year-old diabetic man undergoes an open reduction and internal fixation of a distal tibial fracture through an anterolateral approach. On postoperative day 10, there is wound erythema and superficial dehiscence. He has been smoking 20 cigarettes daily and has HbA1c of 9.5%. The surgical team discusses wound healing biology and factors affecting healing. Regarding wound healing:
Mark each as TRUE or FALSE
Wound healing occurs in four overlapping phases: hemostasis (immediate), inflammation (days 1-5), pr...
The inflammatory phase involves neutrophil infiltration (peak 24-48 hours) for bacterial killing, fo...
The proliferative phase begins at day 21; collagen Type I is produced first, then replaced by Type I...
Factors impairing wound healing include smoking (vasoconstriction, carbon monoxide, impaired oxygen ...
Wound strength increases over time: 3 weeks (20% of normal), 6 weeks (50-60%), never returns to 100%...
Answer the questions to see explanations
Click T (True) or F (False) for each option