Bleeding Disorders
A 28-year-old male with severe hemophilia A (Factor VIII level less than 1%) presents with chronic left knee pain and swelling. He has had multiple hemarthroses since childhood. Examination reveals a warm, swollen knee with 15-degree flexion contracture and limited range of motion. Radiographs show joint space narrowing, subchondral cysts, and epiphyseal overgrowth typical of hemophilic arthropathy. Regarding hemophilic arthropathy:
Mark each as TRUE or FALSE
Hemophilia A (Factor VIII deficiency) and Hemophilia B (Factor IX deficiency, Christmas disease) are...
The pathophysiology of hemophilic arthropathy involves blood-induced synovitis with iron deposition ...
The knee is rarely affected in hemophilia; the hip and spine are the most commonly involved joints; ...
Acute hemarthrosis treatment includes RICE protocol, factor replacement to 40-50% levels, joint aspi...
Synovectomy (open, arthroscopic, or radiosynovectomy with Phosphorus-32 or Yttrium-90) reduces bleed...
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Click T (True) or F (False) for each option