Metabolic Bone Disease
A 55-year-old female presents with vague bone pain and fatigue. Laboratory investigations reveal elevated serum calcium (3.1 mmol/L), low phosphate, elevated PTH, and elevated alkaline phosphatase. Hand radiographs show subperiosteal erosions of the radial aspects of the middle phalanges and distal clavicle resorption. Regarding primary hyperparathyroidism and its skeletal manifestations:
Mark each as TRUE or FALSE
Primary hyperparathyroidism is caused by autonomous PTH secretion (adenoma 85%, hyperplasia 10-15%, ...
Subperiosteal resorption is the pathognomonic radiographic feature of hyperparathyroidism; it is bes...
In primary hyperparathyroidism, PTH levels are suppressed due to high calcium; phosphate is elevated...
Osteitis fibrosa cystica is the advanced skeletal manifestation of hyperparathyroidism characterized...
Brown tumors are non-neoplastic lesions resulting from accelerated osteoclastic activity and hemorrh...
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Click T (True) or F (False) for each option