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General
intermediate
X-Type

Renal Osteodystrophy - Secondary Hyperparathyroidism and Bone Disease

Metabolic Bone Disease

A 58-year-old male with end-stage renal disease on haemodialysis for 5 years presents with diffuse bone pain and proximal muscle weakness. Laboratory tests show elevated PTH (800 pg/mL), low calcium, high phosphate, and low 1,25-dihydroxyvitamin D. Spine radiograph shows alternating bands of sclerosis and lucency. Regarding renal osteodystrophy and secondary hyperparathyroidism:

Mark each as TRUE or FALSE

A

Renal osteodystrophy encompasses the spectrum of bone disease occurring in chronic kidney disease, i...

B

The pathophysiology involves decreased renal 1-alpha-hydroxylase activity leading to reduced 1,25-di...

C

Renal osteodystrophy only causes osteoporosis with no other bone manifestations; PTH levels are typi...

D

The rugger jersey spine describes alternating bands of sclerosis (endplates) and lucency (vertebral ...

E

Other radiographic features include subperiosteal resorption (radial aspect of middle phalanges), br...

Answer the questions to see explanations

Click T (True) or F (False) for each option