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Sickle Cell Disease - Orthopaedic Manifestations

Sickle Cell Disease Orthopaedic

An 18-year-old male with known sickle cell disease (HbSS) presents with severe right hip pain and inability to weight bear. He reports a 3-week history of progressive pain without fever. Examination reveals restricted hip range of motion in all planes with pain on internal rotation. Radiographs show increased density of the femoral head with subtle subchondral lucency. Regarding avascular necrosis (AVN) in sickle cell disease:

Mark each as TRUE or FALSE

A

AVN is the most common orthopaedic complication of sickle cell disease, affecting up to 50% of patie...

B

MRI is the most sensitive imaging modality for early AVN detection, showing bone marrow edema and ch...

C

AVN in sickle cell disease only affects the femoral head and never involves other bones; MRI has no ...

D

Conservative management of sickle cell AVN includes protected weight bearing, pain management, and o...

E

Perioperative management of sickle cell patients includes preoperative transfusion to achieve HbS le...

Answer the questions to see explanations

Click T (True) or F (False) for each option