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Fungal Osteomyelitis - Diagnosis and Management

Musculoskeletal Infections

A 58-year-old patient with acute myeloid leukemia undergoing chemotherapy presents with progressive hip pain over 6 weeks. The patient has been neutropenic for 3 weeks. MRI shows bone marrow edema in the proximal femur with periosteal reaction. Blood cultures and bone biopsy cultures grow Aspergillus fumigatus. Regarding fungal osteomyelitis:

Mark each as TRUE or FALSE

A

Fungal osteomyelitis is most common in immunocompromised patients including those with hematological...

B

Aspergillus osteomyelitis typically occurs via hematogenous spread from pulmonary infection or direc...

C

Fungal osteomyelitis is easily diagnosed on plain radiographs with pathognomonic features; short-cou...

D

Diagnosis of fungal osteomyelitis requires tissue biopsy for histopathology showing fungal elements ...

E

Treatment of Aspergillus osteomyelitis typically requires prolonged antifungal therapy for 6-12 mont...

Answer the questions to see explanations

Click T (True) or F (False) for each option