Metabolic Bone Disease
A 2-year-old child is brought to clinic with bowing of both legs. The mother reports the child has been exclusively breastfed and has had limited sun exposure due to cultural practices. Examination reveals frontal bossing, widened wrists, and bilateral genu varum. X-rays show metaphyseal widening, cupping, and fraying at the distal radius and proximal tibia. Regarding the pathophysiology and classification of rickets:
Mark each as TRUE or FALSE
Rickets is a disorder of defective mineralization of the growth plate (physis) and metaphyseal bone ...
Rickets can be classified as calcipenic (low calcium/vitamin D) or phosphopenic (low phosphate); cal...
Nutritional rickets is rare in developed countries and only occurs with complete absence of sunlight...
Vitamin D metabolism involves hepatic 25-hydroxylation (to 25-OH vitamin D, the storage form) and re...
Clinical features of rickets include skeletal deformities (frontal bossing, rachitic rosary, Harriso...
Answer the questions to see explanations
Click T (True) or F (False) for each option