blood-management-strategies
A 68-year-old woman with a preoperative hemoglobin of 115 g/L is scheduled for primary total knee arthroplasty. She has no history of thromboembolic disease. The anesthesia team asks about tranexamic acid (TXA) administration as part of the patient blood management (PBM) protocol. Regarding tranexamic acid in orthopaedic surgery:
Mark each as TRUE or FALSE
Tranexamic acid is a synthetic lysine analogue that competitively inhibits the conversion of plasmin...
Multiple randomized trials and meta-analyses (including over 20,000 patients) demonstrate TXA does n...
TXA is contraindicated in all patients with coronary artery disease due to increased risk of myocard...
Topical TXA (1-3g in saline applied to the joint before closure) achieves equivalent blood-sparing e...
True contraindications to TXA include active thromboembolic disease, acute kidney injury (reduced cl...
Answer the questions to see explanations
Click T (True) or F (False) for each option