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Basic Science
intermediate
X-Type

Perioperative Antibiotics - Prophylaxis Timing, Redosing, Duration

Surgical Prophylaxis

A 65-year-old male is scheduled for primary total hip arthroplasty. The anaesthetist calls the orthopaedic registrar to confirm the antibiotic prophylaxis protocol. The patient weighs 110kg and has no known drug allergies. Surgery is expected to last approximately 2.5 hours. Regarding perioperative antibiotic prophylaxis timing:

Mark each as TRUE or FALSE

A

Prophylactic antibiotics should be administered within 60 minutes before surgical incision for cepha...

B

Cefazolin is the first-line prophylactic antibiotic for orthopaedic surgery in non-allergic patients...

C

Antibiotic prophylaxis should be given at least 3 hours before surgery for optimal tissue penetratio...

D

Intraoperative redosing of cefazolin should occur if surgery extends beyond 3-4 hours or if blood lo...

E

For patients with documented penicillin allergy, vancomycin (15mg/kg) or clindamycin (900mg) are acc...

Answer the questions to see explanations

Click T (True) or F (False) for each option