Metabolic Complications
A 35-year-old man is brought to the emergency department after being trapped under debris for 6 hours following a building collapse. He is conscious but complains of severe bilateral thigh pain and numbness. His urine appears dark brown. Initial investigations show serum creatine kinase (CK) of 45,000 U/L (normal less than 200), potassium 6.2 mmol/L, creatinine 180 μmol/L, and myoglobin positive on urinalysis. Regarding the pathophysiology and diagnosis of rhabdomyolysis:
Mark each as TRUE or FALSE
Rhabdomyolysis results from skeletal muscle cell injury with release of intracellular contents inclu...
Causes of rhabdomyolysis include crush injury and compartment syndrome, prolonged immobilization, is...
Serum myoglobin is the most sensitive marker for rhabdomyolysis due to its prolonged half-life; crea...
Creatine kinase (CK) is the most sensitive and reliable marker for rhabdomyolysis; levels greater th...
Metabolic derangements in rhabdomyolysis include hyperkalemia (life-threatening arrhythmia risk), hy...
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Click T (True) or F (False) for each option