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Basic Science
intermediate
X-Type

Thromboprophylaxis - VTE Prevention in Orthopaedics

Venous Thromboembolism Prevention

A 68-year-old male is scheduled for elective total hip arthroplasty. His past medical history includes hypertension, type 2 diabetes, and previous peptic ulcer disease (healed). He takes aspirin 100mg for primary cardiovascular prevention. His BMI is 32 and creatinine clearance is 65 mL/min. Regarding pharmacological thromboprophylaxis options following major joint arthroplasty:

Mark each as TRUE or FALSE

A

Low molecular weight heparin (LMWH) such as enoxaparin inhibits factor Xa primarily and factor IIa t...

B

Direct oral anticoagulants (DOACs) approved for VTE prophylaxis after major joint arthroplasty inclu...

C

Aspirin is contraindicated for VTE prophylaxis in all orthopaedic patients; current guidelines unifo...

D

Fondaparinux is a synthetic pentasaccharide that selectively inhibits factor Xa; it has a long half-...

E

For this patient, appropriate prophylaxis options include LMWH 40mg daily, rivaroxaban 10mg daily, o...

Answer the questions to see explanations

Click T (True) or F (False) for each option