Cartilage Repair
A 32-year-old recreational athlete has a 3 cm² focal chondral defect of the medial femoral condyle that failed microfracture. MRI shows ICRS Grade IV full-thickness cartilage loss with subchondral bone intact. He wishes to return to running and cycling. The surgeon recommends autologous chondrocyte implantation (ACI). Regarding autologous chondrocyte implantation:
Mark each as TRUE or FALSE
ACI is a two-stage procedure: first, cartilage biopsy is harvested from a non-weight-bearing area; c...
Ideal indications include focal full-thickness chondral defects (ICRS Grade III-IV) greater than 2 c...
ACI is suitable for generalized osteoarthritis and kissing lesions; subchondral bone damage does not...
MACI (matrix-induced autologous chondrocyte implantation) is third-generation ACI using a collagen s...
Outcomes show 84-90% good to excellent results at 5 years; graft hypertrophy occurs in 5-25% (higher...
Answer the questions to see explanations
Click T (True) or F (False) for each option