Primary Bone Tumors
A 28-year-old man presents with a 2-year history of progressive anterior tibial pain and mild swelling. Radiographs show multiple radiolucent lesions with a "soap bubble" appearance in the anterior tibial cortex extending over 10cm. MRI confirms intracortical location with some medullary involvement. Biopsy reveals a biphasic tumor with epithelial nests and fibrous stroma, positive for cytokeratin on immunohistochemistry. Regarding adamantinoma of bone:
Mark each as TRUE or FALSE
Adamantinoma is a rare low-grade malignant epithelial tumor that occurs almost exclusively in the ti...
The classic radiographic appearance shows multiple radiolucent lesions in the tibial cortex with a "...
Histologically, adamantinoma consists only of spindle cells identical to fibrous dysplasia and is ne...
Adamantinoma has a characteristic biphasic histology with epithelial nests (basaloid, tubular, or sq...
Wide surgical resection (2-3cm margins) is the treatment of choice; local recurrence rates are 15-30...
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Click T (True) or F (False) for each option