Bone Tumors
A 25-year-old man presents with a 6-month history of mild knee pain. Plain radiographs demonstrate an eccentric, well-defined lytic lesion in the proximal tibial metaphysis with endosteal scalloping and a thin sclerotic rim. There is no periosteal reaction or soft tissue mass. MRI shows lobular high T2 signal with peripheral enhancement. Biopsy is performed. Regarding chondromyxoid fibroma:
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Chondromyxoid fibroma (CMF) is the rarest benign cartilaginous tumor, accounting for less than 1% of...
The characteristic radiographic appearance is an eccentric metaphyseal lytic lesion with endosteal s...
CMF has a characteristic histologic pattern with hypercellular center and hypocellular periphery in ...
The histologic hallmark is lobular architecture with hypocellular myxoid center containing sparse st...
Treatment of symptomatic CMF is extended curettage with adjuvants (phenol, cryotherapy, or PMMA ceme...
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