Malignant Tumors
A 52-year-old man presents with a 12-month history of gradually worsening deep thigh pain that is worse at night. He has no history of trauma. Radiographs show a central cartilaginous lesion in the proximal femur with endosteal scalloping involving greater than two-thirds of the cortical thickness, loss of previously documented punctate calcifications, and periosteal reaction. MRI shows marrow replacement with enhancing soft tissue extension. Previous imaging 3 years ago showed a smaller, stable lesion interpreted as an enchondroma. Regarding chondrosarcoma:
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Chondrosarcoma is the second most common primary malignant bone tumor after osteosarcoma; it typical...
Features suggesting malignant transformation of an enchondroma include: pain (especially night pain)...
Chondrosarcoma is most common in children; enchondromas in the hand have a high risk of malignant tr...
Chondrosarcoma grading (1-3) is based on cellularity, nuclear atypia, and mitotic activity: Grade 1 ...
Treatment is primarily surgical with wide resection as chondrosarcoma is resistant to conventional c...
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Click T (True) or F (False) for each option