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OrthoVellum

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Oncology
intermediate
X-Type

Enchondroma and Malignant Transformation

Cartilage Tumours

A 45-year-old woman with known multiple enchondromatosis (Ollier disease) presents with increasing pain in her proximal femur over 6 months. She has had this lesion monitored for years and it was previously stable. Radiographs now show increased size, endosteal scalloping greater than two-thirds cortical thickness, and periosteal reaction. MRI shows a 6cm lesion with areas of soft tissue extension. Regarding enchondroma and malignant transformation:

Mark each as TRUE or FALSE

A

Enchondromas are benign cartilage tumours most common in the hand (50%), typically in the metaphysis...

B

Features suggesting malignant transformation to chondrosarcoma include: new or increasing pain (most...

C

Hand enchondromas have the highest malignant potential; solitary enchondromas transform in 50% of ca...

D

Ollier disease (multiple enchondromatosis) has 25-50% lifetime risk of malignant transformation; Maf...

E

Management of solitary asymptomatic hand enchondroma is observation; curettage and bone grafting for...

Answer the questions to see explanations

Click T (True) or F (False) for each option