Bone Tumors
A 15-year-old boy presents with a 2-month history of progressively worsening pain in his right leg. He has also noticed swelling over his shin and has experienced occasional fevers. Blood tests reveal elevated ESR, CRP, and LDH. Radiographs show a permeative lesion of the mid-diaphysis of the tibia with an "onion skin" periosteal reaction. A soft tissue mass is visible. Regarding Ewing sarcoma:
Mark each as TRUE or FALSE
Ewing sarcoma is the second most common primary malignant bone tumor in children and adolescents aft...
Radiographic features include permeative or moth-eaten bone destruction in the diaphysis, "onion ski...
Ewing sarcoma is most common in patients over 40; metaphyseal location is typical; sclerotic margins...
Histologically, Ewing sarcoma is a small round blue cell tumor with Homer-Wright rosettes; it shows ...
Treatment involves neoadjuvant chemotherapy (vincristine, doxorubicin, cyclophosphamide alternating ...
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Click T (True) or F (False) for each option