Primary Bone Tumors
A 14-year-old boy presents with 3 months of progressive left thigh pain and swelling. He has had intermittent low-grade fevers and feels fatigued. Laboratory studies show elevated ESR and LDH. Radiographs reveal a permeative lesion in the diaphysis of the femur with periosteal reaction described as "onion skinning." MRI shows extensive soft tissue extension. Regarding Ewing sarcoma:
Mark each as TRUE or FALSE
Ewing sarcoma is the second most common primary malignant bone tumor in children and adolescents aft...
Radiographic features include permeative or moth-eaten destruction, aggressive periosteal reaction (...
Ewing sarcoma is most common in adults over 30; epiphyseal location is typical; it is radiosensitive...
Treatment is multimodal: neoadjuvant chemotherapy (vincristine, doxorubicin, cyclophosphamide altern...
Approximately 25% have metastatic disease at presentation (lung most common, then bone and bone marr...
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Click T (True) or F (False) for each option