Benign Bone Tumors
A 32-year-old woman presents with progressive knee pain and swelling over 4 months. Radiographs show an eccentric, lytic lesion in the distal femoral epiphysis extending to the subchondral bone. The lesion has well-defined margins without sclerotic rim or periosteal reaction. There is no matrix mineralization. MRI confirms the lesion abuts the articular surface. Regarding giant cell tumor of bone:
Mark each as TRUE or FALSE
Giant cell tumor (GCT) is a benign but locally aggressive tumor that typically occurs in skeletally ...
Histologically, GCT consists of mononuclear stromal cells (the neoplastic component expressing RANKL...
GCT typically occurs in children under 10 years; it involves the diaphysis, sparing the epiphysis; i...
Campanacci radiographic grading: Grade I (latent - well-marginated, intact cortex), Grade II (active...
Treatment involves extended intralesional curettage with adjuvants (phenol, hydrogen peroxide, liqui...
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Click T (True) or F (False) for each option