Bone Tumors
A 32-year-old woman presents with 4 months of worsening knee pain and swelling. Radiographs show an eccentric, lytic, expansile lesion in the distal femoral epiphysis extending to the subchondral bone. There is no periosteal reaction or soft tissue mass. MRI confirms the lesion and shows no skip lesions. Regarding giant cell tumor of bone:
Mark each as TRUE or FALSE
Giant cell tumor (GCT) is a benign but locally aggressive tumor that typically occurs in skeletally ...
Radiographically, GCT presents as an eccentric, lytic, expansile lesion with well-defined but non-sc...
GCT never metastasizes; all GCTs should be treated with wide resection; denosumab has no role in GCT...
Intralesional curettage with high-speed burr and adjuvant treatment (phenol, hydrogen peroxide, liqu...
Denosumab (anti-RANKL monoclonal antibody) is effective for GCT as the neoplastic stromal cells expr...
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Click T (True) or F (False) for each option