Surgical Oncology
A 16-year-old boy with osteosarcoma of the distal femur has completed neoadjuvant chemotherapy with good response (90% tumor necrosis). MRI shows the tumor is contained within the bone with a small extraosseous component that does not involve the neurovascular bundle. The growth plate is involved but the joint is not invaded. Regarding limb salvage surgery for bone sarcomas:
Mark each as TRUE or FALSE
Limb salvage surgery is now performed in 85-95% of bone sarcoma patients; the goal is wide resection...
Contraindications to limb salvage include: major neurovascular involvement requiring sacrifice, inad...
Limb salvage provides better survival than amputation; margins do not affect outcomes; neurovascular...
Reconstruction options include: endoprosthetic replacement (most common, allows immediate weight-bea...
Endoprosthetic survival is approximately 70-80% at 10 years; complications include infection (5-10%)...
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Click T (True) or F (False) for each option