Metastatic Disease
A 65-year-old woman with known breast cancer presents with progressive right thigh pain worse at night and with weight-bearing. She has no history of trauma. Radiographs show a 4cm lytic lesion in the proximal femoral diaphysis with 60% cortical destruction. Bone scan shows multiple other lesions in the spine and pelvis. Staging CT confirms the femoral lesion is the only long bone at significant risk. Regarding metastatic bone disease:
Mark each as TRUE or FALSE
The most common primary tumours metastasizing to bone are: breast (most common in women), prostate (...
The Mirels scoring system predicts pathologic fracture risk based on four criteria: site (upper limb...
Bone is rarely a site of metastasis; lung cancer typically causes blastic lesions; prostate metastas...
Bisphosphonates (zoledronic acid) and denosumab (RANKL inhibitor) reduce skeletal-related events (pa...
Surgical principles for metastatic bone disease include: assume the entire bone is involved (use loa...
Answer the questions to see explanations
Click T (True) or F (False) for each option