Benign Bone Lesions
A 12-year-old boy presents with incidental finding of a lesion in the distal femur on radiographs obtained after minor trauma. The lesion is eccentric, metaphyseal, and shows a well-defined sclerotic border with a "soap bubble" or multiloculated appearance. There is no periosteal reaction or soft tissue mass. The child is asymptomatic and examination is normal. Regarding non-ossifying fibroma:
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Non-ossifying fibroma (NOF) and fibrous cortical defect (FCD) are the same lesion at different sizes...
Characteristic radiographic features include: eccentric metaphyseal location (long bones, especially...
NOF is a malignant neoplasm requiring aggressive treatment; it occurs in the diaphysis; periosteal r...
Histologically, NOF shows spindle cell fibroblastic tissue in a storiform (whorled) pattern, scatter...
Management is observation for most cases as lesions spontaneously ossify with skeletal maturity; ind...
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