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Oncology
intermediate
X-Type

Osteofibrous Dysplasia - Diagnosis and Management

Bone Tumours

A 4-year-old child is referred with a 6-month history of painless anterior tibial bowing. Radiographs demonstrate an intracortical, ground-glass lesion in the anterior tibial diaphysis with surrounding cortical thickening and expansion. There is anterior bowing of the tibia. The child is otherwise well with no other bony lesions. Regarding osteofibrous dysplasia:

Mark each as TRUE or FALSE

A

Osteofibrous dysplasia is a benign fibro-osseous lesion almost exclusively affecting the anterior co...

B

Osteofibrous dysplasia is cytokeratin NEGATIVE on immunohistochemistry; this distinguishes it from a...

C

Osteofibrous dysplasia is cytokeratin positive which helps distinguish it from fibrous dysplasia; ag...

D

Observation is the preferred treatment for osteofibrous dysplasia as many lesions stabilise or resol...

E

The differential diagnosis includes adamantinoma (older patients, cytokeratin positive), fibrous dys...

Answer the questions to see explanations

Click T (True) or F (False) for each option