Bone Tumours
A 14-year-old boy presents with a 3-month history of progressive knee pain worse at night. Examination reveals a firm mass in the distal femur. Radiographs show a mixed lytic/sclerotic lesion with periosteal reaction and soft tissue extension. Biopsy confirms high-grade conventional osteosarcoma. Staging shows no metastases. Regarding osteosarcoma management:
Mark each as TRUE or FALSE
Osteosarcoma is the most common primary malignant bone tumour in children and adolescents; it has a ...
Neoadjuvant chemotherapy (pre-operative) is standard for high-grade osteosarcoma; the MAP regimen in...
Osteosarcoma is the rarest bone tumour; it peaks in patients over 50 years; diaphysis is the most co...
Histologic response to neoadjuvant chemotherapy is assessed by tumour necrosis: greater than 90% nec...
Surgical resection requires wide margins; limb salvage is achieved in over 80% of cases with modern ...
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Click T (True) or F (False) for each option