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Oncology
intermediate
X-Type

Osteosarcoma Diagnosis and Treatment

Bone Tumors

A 14-year-old boy presents with a 3-month history of progressive knee pain and a palpable, firm mass in the distal thigh. Pain is worse at night and not relieved by rest. Radiographs show a destructive lesion of the distal femur with periosteal reaction (Codman triangle) and sunburst pattern. Serum alkaline phosphatase is elevated. Regarding osteosarcoma:

Mark each as TRUE or FALSE

A

Osteosarcoma is the most common primary malignant bone tumor in children and adolescents; the classi...

B

Radiographic features include metaphyseal destructive lesion with permeative or moth-eaten pattern, ...

C

Osteosarcoma is most common in patients over 60 years; diaphyseal location is typical; chondroid mat...

D

Treatment involves neoadjuvant chemotherapy (methotrexate, doxorubicin, cisplatin) for 8-12 weeks to...

E

Biopsy should be planned by the treating surgeon to ensure the biopsy tract can be excised en bloc; ...

Answer the questions to see explanations

Click T (True) or F (False) for each option