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Oncology
intermediate
X-Type

Osteosarcoma Management Principles

Primary Bone Tumours

A 16-year-old boy presents with a 3-month history of progressive knee pain and swelling. Radiographs show an aggressive lesion of the distal femoral metaphysis with periosteal reaction and soft tissue extension. MRI confirms a 12cm intramedullary lesion with cortical destruction and soft tissue mass. Staging CT chest shows no pulmonary metastases. Biopsy confirms high-grade conventional osteosarcoma. Regarding osteosarcoma:

Mark each as TRUE or FALSE

A

Osteosarcoma is the most common primary malignant bone tumour in adolescents (second overall after m...

B

The Enneking (Musculoskeletal Tumor Society) staging system: Stage IA (low-grade, intracompartmental...

C

Osteosarcoma is most common in the diaphysis of long bones; chondrosarcoma is more common than osteo...

D

Standard treatment includes neoadjuvant (preoperative) chemotherapy, surgery (limb salvage or amputa...

E

Limb salvage surgery is possible in 80-90% of cases with equivalent survival to amputation when adeq...

Answer the questions to see explanations

Click T (True) or F (False) for each option