Primary Bone Tumors
A 14-year-old boy presents with 3 months of progressive right distal femur pain and swelling. Radiographs show an aggressive mixed lytic/scite lesion with periosteal reaction and soft tissue extension. MRI confirms a large tumor with cortical breakthrough. Biopsy reveals high-grade conventional osteosarcoma. Staging CT shows no pulmonary metastases. Regarding osteosarcoma treatment:
Mark each as TRUE or FALSE
Standard treatment for high-grade osteosarcoma is neoadjuvant chemotherapy (MAP regimen: Methotrexat...
Surgical margins: wide resection (2cm or intact fascial barrier) is the goal; intralesional (through...
Amputation always has better survival than limb salvage surgery; neoadjuvant chemotherapy is not use...
Huvos grading assesses tumor necrosis after neoadjuvant chemotherapy: Grade I (less than 50% necrosi...
Limb salvage reconstruction options include: endoprosthetic replacement (most common, allows early m...
Answer the questions to see explanations
Click T (True) or F (False) for each option