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Oncology
intermediate
X-Type

Periosteal Osteosarcoma

Bone Sarcomas

A 19-year-old male presents with a slowly growing, mildly painful mass on the anterior aspect of his mid-femur that he noticed 6 months ago. Examination reveals a firm, fixed mass over the anterior tibial diaphysis. Radiographs show a surface-based lesion arising from the diaphyseal cortex with "sunburst" periosteal reaction and a soft tissue mass; the medullary cavity appears uninvolved. CT confirms cortical scalloping without medullary extension. Biopsy reveals intermediate-grade cartilaginous and osteoid matrix with moderate atypia. Regarding periosteal osteosarcoma:

Mark each as TRUE or FALSE

A

Periosteal osteosarcoma is a rare surface (juxtacortical) osteosarcoma arising from the periosteal s...

B

The three juxtacortical osteosarcomas are: parosteal (low-grade, arises from outer periosteum, metap...

C

Periosteal osteosarcoma is the most common osteosarcoma subtype; it arises from the medullary cavity...

D

Imaging features: surface-based lesion on the diaphyseal cortex, perpendicular "sunburst" or "hair-o...

E

Treatment: wide surgical resection is the mainstay; the role of chemotherapy is debated - some cente...

Answer the questions to see explanations

Click T (True) or F (False) for each option