Soft Tissue Tumors
A 55-year-old man presents with a 10cm painless mass in his anterior thigh that has been slowly enlarging over 6 months. MRI shows a deep-seated heterogeneous mass with areas of necrosis. Core needle biopsy reveals a high-grade pleomorphic sarcoma. Staging CT of the chest shows no pulmonary metastases. The tumor is deep to fascia and abuts but does not invade the femoral vessels. Regarding soft tissue sarcoma staging and treatment:
Mark each as TRUE or FALSE
The AJCC staging system incorporates tumor grade (G1-3 based on differentiation, mitotic rate, necro...
Surgical margins are critical: R0 (negative microscopic margin, target greater than 1cm when possibl...
Tumor size is the most important prognostic factor; grade is irrelevant; superficial tumors are wors...
Radiation therapy (neoadjuvant or adjuvant) improves local control, particularly for high-grade, dee...
Prognosis depends on stage: Stage I (low grade, any size) has greater than 90% 5-year survival; Stag...
Answer the questions to see explanations
Click T (True) or F (False) for each option