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OrthoVellum

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Oncology
intermediate
X-Type

Telangiectatic Osteosarcoma

Bone Tumors

A 16-year-old boy presents with a 6-week history of progressively worsening thigh pain and swelling. He denies any trauma. Radiographs show a purely lytic, expansile lesion of the distal femur with cortical destruction and minimal periosteal reaction. MRI reveals multiple fluid-fluid levels within the lesion. Biopsy is performed. The pathologist notes blood-filled cystic spaces with highly malignant cells in the cyst walls, positive for osteoid production. Regarding telangiectatic osteosarcoma:

Mark each as TRUE or FALSE

A

Telangiectatic osteosarcoma is a rare high-grade variant accounting for approximately 4% of all oste...

B

Radiographically, telangiectatic osteosarcoma appears as a purely lytic, destructive lesion often wi...

C

Telangiectatic osteosarcoma is a low-grade tumor with excellent prognosis; it shows dense osteoid ma...

D

The differential diagnosis includes aneurysmal bone cyst, giant cell tumor, simple bone cyst, and ot...

E

Treatment follows the same protocol as conventional high-grade osteosarcoma: neoadjuvant chemotherap...

Answer the questions to see explanations

Click T (True) or F (False) for each option