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OrthoVellum

© 2026 OrthoVellum. For educational purposes only.

Not affiliated with the Royal Australasian College of Surgeons.

Special
Intermediate
High Yield

Upper Limb Peripheral Nerve Examination

Focused examination of individual upper limb peripheral nerves including median, ulnar, radial, and musculocutaneous nerves with specific motor and sensory testing.

Upper Limb Peripheral Nerve Examination

Examiner Favorite

Peripheral nerve examination requires knowledge of individual nerve motor and sensory territories. Examiners expect you to differentiate between median, ulnar, and radial nerve lesions based on examination findings, and to localize the level of injury (high vs low lesion).

Quick Reference One-Pager

Upper Limb Peripheral Nerves Summary

High-Yield Exam Summary

Median Nerve

  • •Motor: LOAF (Lumbricals 1-2, Opponens, APB, FPB superficial)
  • •High lesion adds: FDS, FDP (IF), FCR, PT, PQ
  • •Sensory: Palmar lateral 3.5 digits
  • •Test: OK sign, opposition, pulp of index

Ulnar Nerve

  • •Motor: All intrinsics EXCEPT LOAF
  • •High lesion adds: FCU, FDP (RF, SF)
  • •Sensory: 1.5 digits ulnar (palmar + dorsal)
  • •Test: Finger abduction, Froment's, little finger pulp

Radial Nerve

  • •Motor: All extensors (wrist, fingers, thumb)
  • •High lesion adds: Triceps
  • •Sensory: First dorsal web space
  • •Test: Wrist drop, finger extension, thumb retropulsion

Injury Levels

  • •High: Above elbow
  • •Low: At wrist/hand
  • •Pattern differs based on level

Median Nerve

Muscles Supplied:

At/Below Wrist (LOAF):

  • Lumbricals 1 and 2
  • Opponens pollicis
  • Abductor pollicis brevis (APB)
  • Flexor pollicis brevis (superficial head)

Above Wrist (Anterior Interosseous - AIN):

  • Flexor pollicis longus (FPL)
  • Flexor digitorum profundus (index and middle)
  • Pronator quadratus

In Forearm (High Lesion):

  • Pronator teres
  • Flexor carpi radialis
  • Palmaris longus
  • Flexor digitorum superficialis
  • Above plus AIN muscles

Palmar Surface:

  • Lateral 3.5 digits (thumb to radial half ring finger)
  • Palm over thenar eminence
  • Palmar cutaneous branch arises proximal to carpal tunnel

Dorsal Surface:

  • Distal phalanges of lateral 3.5 digits
  • Fingertips only (not back of hand)

Key Test Point:

  • Index finger pulp (most reliable)

High Median Nerve Lesion:

  • Hand of Benediction (trying to make fist)
  • Cannot flex IPJ thumb and DIP index/middle
  • Loss of forearm pronation

Low Median Nerve Lesion (at wrist):

  • Thenar wasting (ape hand deformity)
  • Weak thumb opposition
  • Sensory loss palm and digits

Anterior Interosseous Syndrome:

  • Pure motor (no sensory loss)
  • Cannot make OK sign

Median Motor Testing - Opposition

Test APB and opponens pollicis

Technique

  1. 1Ask patient to touch thumb tip to little finger tip
  2. 2Thumb should rotate (not just adduct)
  3. 3Resist patient trying to maintain position
Positive Sign

Weak or absent opposition

Indicates

Median nerve motor deficit (LOAF muscles)

Diagnostic Accuracy

Sensitivity85%

Ability to detect true positives

Specificity90%

Ability to exclude false positives

OK Sign Test

Test anterior interosseous nerve function

Technique

  1. 1Ask patient to make 'OK' sign
  2. 2Index and thumb should form a circle with flexed DIP/IPJ
Positive Sign

Triangle sign (flat index DIP, flat thumb IPJ) instead of circle

Indicates

Anterior interosseous syndrome - FPL and index FDP weakness

Diagnostic Accuracy

Sensitivity90%

Ability to detect true positives

Specificity95%

Ability to exclude false positives

Ulnar Nerve

Muscles Supplied (All Intrinsics Except LOAF):

Hand Muscles:

  • Interossei (all 4 dorsal, all 3 palmar)
  • Lumbricals 3 and 4
  • Adductor pollicis
  • Flexor pollicis brevis (deep head)
  • Hypothenar muscles (ADM, ODM, FDM)

Forearm (High Lesion Only):

  • Flexor carpi ulnaris (FCU)
  • Flexor digitorum profundus (ring and little fingers)

Distribution:

  • Medial 1.5 digits (little finger + ulnar half ring)
  • BOTH palmar AND dorsal surfaces

Key Test Point:

  • Little finger pulp

Dorsal Branch:

  • Arises 5cm proximal to wrist
  • Sensory to dorsal medial hand
  • Spared in wrist-level injury

High Ulnar Nerve Lesion:

  • Ulnar claw LESS pronounced (ulnar paradox)
  • FCU and ulnar FDP also weak
  • Cannot flex DIP ring/little fingers

Low Ulnar Nerve Lesion (at wrist/hand):

  • Ulnar claw deformity MORE pronounced
  • MCP hyperextension, IPJ flexion (ring, little)
  • Intrinsic minus posture
  • Dorsal cutaneous sensation may be SPARED

Ulnar Paradox:

  • High lesion = less clawing (FDP paralyzed too)
  • Low lesion = more clawing (FDP works, pulls IPJ into flexion)

Froment's Sign

Test adductor pollicis (ulnar nerve)

Technique

  1. 1Patient grips paper between thumb and side of index finger
  2. 2Pull paper away
  3. 3Observe thumb position
Positive Sign

Flexion of thumb IPJ (using FPL instead of weak adductor pollicis)

Indicates

Ulnar nerve palsy with adductor pollicis weakness

Diagnostic Accuracy

Sensitivity82%

Ability to detect true positives

Specificity98%

Ability to exclude false positives

Finger Abduction Test

Test dorsal interossei (ulnar nerve)

Technique

  1. 1Patient spreads fingers apart (abduction)
  2. 2Examiner attempts to push fingers together
Positive Sign

Weakness of finger abduction compared to other side

Indicates

Ulnar nerve palsy - dorsal interosseous weakness

Diagnostic Accuracy

Sensitivity88%

Ability to detect true positives

Specificity92%

Ability to exclude false positives

Wartenberg Sign

Test ulnar nerve function

Technique

  1. 1Patient extends fingers straight
  2. 2Observe position of little finger
Positive Sign

Little finger abducted, cannot be held adducted

Indicates

Ulnar nerve palsy - weak third palmar interosseous

Diagnostic Accuracy

Sensitivity80%

Ability to detect true positives

Specificity85%

Ability to exclude false positives

Radial Nerve

Muscles Supplied:

In Arm (High Lesion):

  • Triceps
  • Brachioradialis
  • ECRL (may be spared as branch early)

In Forearm:

  • ECRB
  • Supinator
  • Extensor digitorum communis
  • Extensor digiti minimi
  • Extensor carpi ulnaris
  • Abductor pollicis longus
  • Extensor pollicis brevis
  • Extensor pollicis longus
  • Extensor indicis

Posterior Interosseous Nerve (PIN):

  • Pure motor branch
  • All extensors below supinator

Distribution:

  • Posterior arm and forearm (radial nerve proper)
  • Dorsum of hand, lateral 3.5 digits (superficial radial)

Key Test Point:

  • First dorsal web space

Superficial Radial Nerve:

  • Pure sensory
  • Emerges from under brachioradialis
  • Dorsum of hand sensory

High Radial Nerve Palsy (Spiral Groove):

  • Wrist drop
  • Finger drop
  • Loss of thumb extension
  • Weak brachioradialis (elbow flexion)
  • Triceps SPARED (branch proximal)

PIN Syndrome (Forearm):

  • Pure motor (no sensory loss)
  • Finger drop
  • Weak wrist extension (ECU weak, but ECRL works)
  • Wrist deviates radially on extension
  • No wrist drop

Superficial Radial Nerve:

  • Pure sensory
  • First web space numbness
  • No motor loss

Wrist Drop Test

Test radial nerve function

Technique

  1. 1Ask patient to extend wrist against gravity
  2. 2Arms out, palms facing floor
  3. 3Compare sides
Positive Sign

Wrist drops, cannot extend against gravity

Indicates

High radial nerve palsy

Diagnostic Accuracy

Sensitivity95%

Ability to detect true positives

Specificity98%

Ability to exclude false positives

Finger Extension Test

Test PIN or radial nerve

Technique

  1. 1Hold wrist in neutral (supported)
  2. 2Ask patient to extend MCP joints of fingers
Positive Sign

Cannot extend fingers at MCP joints

Indicates

Radial nerve (high) or PIN (low) lesion

Diagnostic Accuracy

Sensitivity92%

Ability to detect true positives

Specificity95%

Ability to exclude false positives

EPL Test (Retropulsion)

Test extensor pollicis longus

Technique

  1. 1Place palm flat on table
  2. 2Ask patient to lift thumb straight up off surface
Positive Sign

Cannot lift thumb off table

Indicates

EPL rupture or radial nerve/PIN lesion

Diagnostic Accuracy

Sensitivity95%

Ability to detect true positives

Specificity98%

Ability to exclude false positives

Musculocutaneous Nerve

Anatomy and Function

Motor:

  • Biceps brachii (main elbow flexor and supinator)
  • Brachialis
  • Coracobrachialis

Sensory:

  • Lateral cutaneous nerve of forearm
  • Lateral forearm sensation

Clinical Features of Lesion:

  • Weak elbow flexion (biceps and brachialis)
  • Weak supination
  • Numbness lateral forearm
  • Absent biceps reflex

Distinguishing Lesion Levels

nervehighLesionlowLesion
MedianHand of Benediction, no FPL/index FDPThenar wasting, weak opposition only
UlnarLess claw, no FCU/ulnar FDPWorse claw, dorsal sensation may be spared
RadialWrist drop + finger dropFinger drop only (PIN), or sensory only (superficial)
Key Concept

Quick Differentiation:

  • Can't make fist (IF, MF) = Median (high)
  • Can't spread fingers = Ulnar
  • Can't extend wrist/fingers = Radial
  • Can't flex elbow = Musculocutaneous

Sensory Key Points:

  • Index pulp = Median
  • Little finger pulp = Ulnar
  • First web space dorsum = Radial

Combined Lesions

Brachial Plexus Patterns

Upper Trunk (Erb's C5-6):

  • Weak shoulder abduction, external rotation
  • Weak elbow flexion
  • Waiter's tip posture

Lower Trunk (Klumpke's C8-T1):

  • Intrinsic hand weakness
  • Ulnar sensory loss
  • May have Horner's syndrome

Posterior Cord:

  • Radial + axillary nerves
  • Wrist drop + weak shoulder abduction

Summary Presentation

VIVA SCENARIOStandard

Presenting Your Findings

EXAMINER

"35-year-old man presents 3 months after humeral shaft fracture with inability to extend wrist."

KEY POINTS TO SCORE
Spiral groove palsy: Wrist drop + finger drop, triceps spared
Test triceps to differentiate high from very high lesion
Superficial radial sensory loss = first web space dorsum
10% of humeral shaft fractures have radial nerve palsy
COMMON TRAPS
✗Confusing radial with PIN lesion (PIN has no sensory loss)
✗Missing preserved triceps (helps localize level)
✗Not splinting to prevent wrist flexion contracture
✗Forgetting that radial nerve may recover spontaneously in closed fractures

Examination Sequence

Systematic Approach

  1. Inspection: Wasting, deformity, trophic changes
  2. Median motor: Opposition, APB, OK sign
  3. Ulnar motor: Finger abduction, Froment's, Wartenberg
  4. Radial motor: Wrist extension, finger extension, EPL
  5. Median sensory: Index finger pulp
  6. Ulnar sensory: Little finger pulp, dorsal (check level)
  7. Radial sensory: First dorsal web space
  8. Reflexes: Biceps, triceps
  9. Compare sides: Every finding
  10. Localize level: High vs low based on pattern

Examiner Tips

Scoring High in Peripheral Nerve Examination

High-Yield Exam Summary

Do

  • •Know key muscles for each nerve (LOAF for median)
  • •Test sensory at key points (index, little, 1st web)
  • •Distinguish high from low lesions
  • •Know Froment's sign technique and meaning
  • •Compare systematically with other side

Don't

  • •Confuse dermatomal with peripheral nerve pattern
  • •Miss the ulnar paradox concept
  • •Forget to test triceps in radial nerve (localizes level)
  • •Miss the dorsal cutaneous branch sparing in wrist-level ulnar
  • •Overlook PIN syndrome (motor only, no sensory loss)
Quick Reference
Time Allocation5 min
Joint/RegionUpper Limb
Typefocused
Updated2025-12-26
Examination Framework
  • Look - Inspection
  • Feel - Palpation
  • Move - ROM & Power
  • Special Tests
  • Neurovascular
Tags
peripheral-nerve
median
ulnar
radial
musculocutaneous
nerve-injury
Related Examinations
  • hand nerve examination
  • upper limb neurology