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Evidence. Clarity. Practice.

Β© 2026 OrthoVellum. For educational purposes only.

Not medical advice. Verify clinically important information against current local guidance.

MIPO Anterior Humeral Corridor

Operative SurgeryTrauma
TraumaAdvancedCore Procedure

MIPO Anterior Humeral Corridor

Comprehensive guide to minimally invasive plate osteosynthesis (MIPO) via the anterior humeral corridor for bridge plating of humeral shaft fractures - supine positioning, deltopectoral and anterolateral windows, the brachialis protecting the radial nerve, and submuscular plate tunnelling for Orthopaedic exam

Procedure console
24 min
Read
0
Sections
advanced
Level
Peer-reviewed Β· 2026-06-20
High-yield overview

Supine | Two Windows | Brachialis Protects the Radial Nerve

SupinePatient position
2 windowsDeltopectoral proximal, anterolateral distal
BrachialisMuscular buffer protecting the radial nerve
Long plateBridge construct, low screw density
Critical Must-Knows
  • Supine position with the whole humerus visible to fluoroscopy in AP and lateral
  • Two incisions only β€” a proximal deltopectoral and a distal anterolateral window; the fracture haematoma is never touched
  • The brachialis is the key protective layer β€” splitting it leaves a lateral cuff shielding the radial nerve
  • Submuscular extrasynovial tunnelling of a long pre-contoured bridge plate preserves biology
  • Indirect reduction restores length, alignment and rotation; the plate is a reduction tool, not an anatomic clamp

When & Why


What it exposes. The anterior MIPO corridor delivers a long submuscular bridge plate to the humeral shaft through two small windows β€” a proximal deltopectoral window and a distal anterolateral window β€” joined by an extrasynovial, epiperiosteal tunnel on the anterior cortex, with no direct exposure of the fracture. Primary indications: - Comminuted or segmental humeral shaft fractures where biological preservation favours bridge plating over rigid compression

  • Unstable shaft fractures unsuitable for non-operative management (shortening, angulation, displacement, or failure of functional bracing)
  • Pathological or impending pathological fractures of the humeral diaphysis
  • Polytrauma where early definitive or damage-control stabilisation is desirable
  • Selected open fractures with soft-tissue compromise where long extensile incisions are best avoided
  • Paediatric and adolescent humeral shaft fractures in selected cases where fixation is indicated Why this approach is chosen. MIPO respects the biological environment at the fracture by avoiding direct exposure of the fracture haematoma and the soft-tissue attachments. A long plate is slid through two small windows along the anterior humeral surface, which is broad, relatively flat and largely submuscular. This delivers a long, elastic bridge construct that distributes strain and supports indirect healing, in contrast to open plating (which strips biology) or intramedullary nailing (which carries distinct shoulder entry-point and radial-nerve considerations). Contraindications: - Intra-articular extension requiring direct open reduction (use a formal articular approach instead)
  • Active wound infection or gross contamination over the planned windows (until controlled)
  • Fracture patterns where the radial nerve is interposed between fragments and must be directly visualised (some surgeons prefer a posterior approach with nerve identification)
  • Vascular injury requiring open exploration and repair
  • Inability to obtain adequate fluoroscopic imaging of the whole humerus intra-operatively
Functional bracing
Approach
Non-operative
Biology at fracture
Maximal
Key trade-off
Needs a compliant patient and acceptable alignment
MIPO bridge plating
Approach
Two small windows, supine
Biology at fracture
Preserved
Key trade-off
Fluoroscopic; radial nerve caution
Intramedullary nailing
Approach
Closed, shoulder entry
Biology at fracture
Preserved
Key trade-off
Shoulder pain and rotator cuff entry morbidity
Open ORIF
Approach
Formal exposure
Biology at fracture
Reduced
Key trade-off
Direct visualisation, higher soft-tissue insult
Humeral shaft fixation β€” options compared
MethodApproachBiology at fractureKey trade-off
Functional bracingNon-operativeMaximalNeeds a compliant patient and acceptable alignment
MIPO bridge platingTwo small windows, supinePreservedFluoroscopic; radial nerve caution
Intramedullary nailingClosed, shoulder entryPreservedShoulder pain and rotator cuff entry morbidity
Open ORIFFormal exposureReducedDirect visualisation, higher soft-tissue insult

Position & landmarks. The supine position is central to the anterior MIPO corridor. Place the patient supine on a radiolucent table with a small bolster under the ipsilateral scapula to bring the arm forward, and rest the arm on a radiolucent armboard or across the chest on a sterile bolster. The aim is unobstructed fluoroscopic visualisation of the entire humerus in AP and lateral β€” confirm both views before draping. A well-padded tourniquet is used only if it will not obstruct plate length or imaging; many surgeons operate without one. Proximal window landmarks: the coracoid process (palpable guide to the deltopectoral interval), the anterolateral corner of the acromion (proximal extent for a deltoid-splitting variant), the deltopectoral groove containing the cephalic vein, and the long head of biceps tendon in the intertubercular groove. Distal window landmarks: the biceps brachii muscle belly and tendon (the medial boundary, retracted medially), the lateral supracondylar ridge and lateral epicondyle, the mobile wad (brachioradialis and extensor carpi radialis longus and brevis) marking where the radial nerve lies, and the brachialis filling the interval between biceps and the lateral musculature.

The Exposure


Work from two windows remote from the fracture, develop an internervous plane at each, and join them with a submuscular tunnel on the anterior cortex. The broad, flat anterior humeral surface is the plate-bearing surface, and the brachialis is the muscular buffer that shields the radial nerve throughout.

Proximal
Muscle
Deltoid
Nerve supply
Axillary nerve
Role in the approach
Retracted laterally in the proximal window
Proximal
Muscle
Pectoralis major
Nerve supply
Lateral pectoral nerve
Role in the approach
Retracted medially in the proximal window
Anterior
Muscle
Biceps brachii
Nerve supply
Musculocutaneous nerve
Role in the approach
Retracted medially in the distal window
Anterior (deep)
Muscle
Brachialis
Nerve supply
Musculocutaneous and radial nerves
Role in the approach
Split in its mid-substance β€” the lateral half protects the radial nerve
Lateral (distal)
Muscle
Brachioradialis and ECRL
Nerve supply
Radial nerve
Role in the approach
Marks the lateral border near the radial nerve
Muscular layers of the anterior corridor
LayerMuscleNerve supplyRole in the approach
ProximalDeltoidAxillary nerveRetracted laterally in the proximal window
ProximalPectoralis majorLateral pectoral nerveRetracted medially in the proximal window
AnteriorBiceps brachiiMusculocutaneous nerveRetracted medially in the distal window
Anterior (deep)BrachialisMusculocutaneous and radial nervesSplit in its mid-substance β€” the lateral half protects the radial nerve
Lateral (distal)Brachioradialis and ECRLRadial nerveMarks the lateral border near the radial nerve

Two internervous planes, one tunnel. The proximal window uses the deltopectoral interval β€” deltoid (axillary nerve) versus pectoralis major (pectoral nerves). The distal window runs between biceps (musculocutaneous nerve), retracted medially, and the underlying brachialis; the brachialis is then split longitudinally to bone. This split is safe because the brachialis has dual innervation β€” the medial half from the musculocutaneous nerve and the lateral half from the radial nerve β€” so neither half is denervated. Leaving the lateral half of brachialis attached interposes muscle between the plate and the radial nerve, which lies further lateral, between brachialis and brachioradialis.

Exposure sequence

Step 1Position and confirm fluoroscopy
  • Position the patient supine on a radiolucent table with the ipsilateral scapula boosted and the arm free on an armboard.
  • Confirm full AP and lateral fluoroscopy of the entire humerus before draping; test the C-arm from both sides.
  • Assess reduction and rotation with the image β€” for the lateral view, rotate the arm and align the humeral head with the epicondyles to judge rotation.
Step 2Plan and make the two incisions
  • Proximal incision: a 4 to 6 cm deltopectoral incision from just below the coracoid distally along the groove (or a short anterolateral deltoid-splitting incision off the acromion for a more lateral proximal plate).
  • Distal incision: a 4 to 6 cm anterolateral incision over the distal humerus, centred on the biceps-to-brachioradialis interval.
  • Both incisions are deliberately kept remote from the fracture so the fracture biology is never disturbed.
Step 3Proximal window β€” deltopectoral interval
  • Deepen the proximal incision through subcutaneous fat to the deltopectoral groove; identify the cephalic vein and protect or ligate it as required.
  • Retract deltoid laterally and pectoralis major medially to expose the anterior proximal humerus and the long head of biceps tendon in its groove.
  • Elevate a plane directly on bone, deep to deltoid, creating the entry for the proximal end of the plate on the anterolateral proximal humerus; stay on bone and avoid straying distal and posterior where the axillary nerve wraps the surgical neck.
Step 4Distal window β€” biceps to brachialis, then split the brachialis
  • Deepen the distal incision through subcutaneous tissue and the deep fascia over the biceps-to-brachioradialis interval.
  • Gently retract biceps medially; the musculocutaneous nerve and its continuation as the lateral antebrachial cutaneous nerve lie between biceps and brachialis β€” protect them by staying on the brachialis.
  • Incise the brachialis longitudinally in its mid-substance down to bone; retract the medial half with biceps and leave the lateral half attached laterally.
  • Elevate the brachialis off the anterior shaft subperiosteally to create the distal end of the tunnel β€” the lateral brachialis cuff now interposes between the plate and the radial nerve.
Step 5Create the submuscular tunnel and pass the plate
  • From the distal window, slide a periosteal elevator along the anterior humeral shaft, deep to brachialis and deltoid, strictly on bone, to reach the proximal window β€” an extrasynovial, epiperiosteal tunnel on the anterior cortex.
  • Select a long, pre-contoured anterior humeral plate and bridge the fracture with widely spaced screws (long plate, low screw density).
  • Attach the plate to the elevator or a plate-passer and slide it through the tunnel, confirming position on the anterior humerus with fluoroscopy in both planes; verify it sits centrally on the shaft at the fracture and at both ends.
Step 6Indirect reduction, fixation and closure
  • Restore length, alignment and rotation indirectly using traction, percutaneous pointed reduction clamps and the plate itself as a template; blocking (poller) screws correct residual translation. The fracture haematoma is never opened.
  • Hold with one screw proximal and one distal, then place a minimum of three bicortical screws proximal and three distal, spread along the plate (locking screws in the metaphysis, cortical screws in the diaphysis as bone quality dictates).
  • Irrigate both windows; no deep closure is needed because brachialis and deltoid fall back over the plate. Close the fascia, subcutaneous tissue and skin in layers and apply a soft dressing with a sling or splint.
The brachialis is the buffer β€” never stray lateral to it

The radial nerve runs lateral to the brachialis, between the brachialis and the brachioradialis and extensor carpi radialis longus, in the distal third of the arm. It spirals in the radial groove posteriorly and pierces the lateral intermuscular septum roughly 10 cm proximal to the lateral epicondyle. By splitting the brachialis and keeping every instrument strictly on the anterior cortex, the intact lateral half of brachialis shields the radial nerve from the plate. Straying lateral to the brachialis, or working off bone, puts the radial nerve directly at risk.

The plate is a reduction tool, not a clamp

Reduction is entirely indirect and fluoroscopic. Confirm true AP and lateral views of the whole humerus, restore length, alignment and rotation with traction and clamps, and use blocking screws for residual translation β€” the fracture haematoma is left completely undisturbed. This biology-preserving, elastic bridge construct is designed to heal by callus rather than fail by hardware.

Dangers & Extensions


Structures at risk, by layer

Proximal window
Structure at risk
Axillary nerve (anterior branch)
Protection
Keep any deltoid split proximal; stay on bone under the deltoid
Proximal window
Structure at risk
Cephalic vein
Protection
Identify in the groove; protect or ligate branches
Tunnel and distal window
Structure at risk
Radial nerve
Protection
Keep the lateral brachialis cuff intact; stay epiperiosteal on the shaft
Distal window
Structure at risk
Musculocutaneous and lateral antebrachial cutaneous nerves
Protection
Retract biceps medially; stay lateral to biceps on the brachialis
Distal window
Structure at risk
Brachial artery and median nerve
Protection
Do not stray medial to biceps
Danger structures and how to protect them
WindowStructure at riskProtection
Proximal windowAxillary nerve (anterior branch)Keep any deltoid split proximal; stay on bone under the deltoid
Proximal windowCephalic veinIdentify in the groove; protect or ligate branches
Tunnel and distal windowRadial nerveKeep the lateral brachialis cuff intact; stay epiperiosteal on the shaft
Distal windowMusculocutaneous and lateral antebrachial cutaneous nervesRetract biceps medially; stay lateral to biceps on the brachialis
Distal windowBrachial artery and median nerveDo not stray medial to biceps
Radial nerve

The most feared structure. It spirals in the radial groove on the posterior shaft, pierces the lateral intermuscular septum roughly 10 cm proximal to the lateral epicondyle, then runs between brachialis and brachioradialis. It is protected by keeping the lateral half of brachialis intact and by sliding the plate strictly on the anterior cortex. Injury causes wrist drop and loss of finger and thumb extension.

Axillary nerve

The anterior branch wraps the surgical neck of the humerus under the deltoid and is at risk in the proximal window if a deltoid split is extended too far distally. Keep the deltoid split proximal (within roughly 5 cm of the acromion) and stay on bone subdeltoid.

Musculocutaneous nerve

Runs between biceps and brachialis and emerges at the elbow as the lateral antebrachial cutaneous nerve. It is at risk in the distal window if dissection strays medial to biceps β€” protect by retracting biceps medially and working on the brachialis.

Cephalic vein

Lies in the deltopectoral groove. Identify it in the proximal window; small branches are coagulated and the main trunk is protected or sacrificed as needed for exposure.

Radial nerve injury management: - Document pre-operative radial nerve function (wrist and finger extension, first web sensation) on every patient.

  • If the nerve is identified as injured intra-operatively, visualise it and repair or graft as appropriate.
  • A new post-operative palsy: remove constrictive dressings, exclude a compressive cause, document and observe; obtain electromyography at three to four weeks and consider exploration if there is no recovery by the expected timeframe.
  • Most traction neurapraxias recover; a persistent complete palsy may require tendon transfers. Extensile modifications. Extend the deltopectoral window proximally for proximal humeral involvement, or use a deltoid-splitting anterolateral acromial approach to reach the proximal humeral head and greater tuberosity (beware the axillary nerve wrapping the surgical neck β€” stay proximal and on bone). Extend the anterolateral window distally along the Henry approach toward the elbow for distal-third fractures, where the radial nerve can be formally identified and protected as it emerges between brachialis and brachioradialis. Segmental fractures suit MIPO well, as one long plate spans multiple zones without exposure; intra-articular extension requires a separate formal open approach rather than continuing the corridor. Complications
Iatrogenic radial nerve palsy
Prevention
Keep the lateral brachialis cuff intact; slide the plate strictly on bone
Management
Document, observe, EMG; explore if no recovery
Malreduction (varus, extension, rotation)
Prevention
True AP and lateral fluoroscopy; use the plate and blocking screws
Management
Revise fixation if alignment is unacceptable
Axillary nerve injury (proximal)
Prevention
Keep the deltoid split proximal; stay subdeltoid on bone
Management
Observe; most recover
Plate malposition (posterior, medial)
Prevention
Confirm plate-on-bone in both planes before fixation
Management
Reposition and re-fixate
Intra-operative complications
ComplicationPreventionManagement
Iatrogenic radial nerve palsyKeep the lateral brachialis cuff intact; slide the plate strictly on boneDocument, observe, EMG; explore if no recovery
Malreduction (varus, extension, rotation)True AP and lateral fluoroscopy; use the plate and blocking screwsRevise fixation if alignment is unacceptable
Axillary nerve injury (proximal)Keep the deltoid split proximal; stay subdeltoid on boneObserve; most recover
Plate malposition (posterior, medial)Confirm plate-on-bone in both planes before fixationReposition and re-fixate
Iatrogenic radial nerve palsy
Incidence
Low with correct technique
Prevention
Brachialis protection, stay on bone
Treatment
Observation, EMG, explore if persistent
Nonunion
Incidence
Low
Prevention
Biological bridge plating, stable construct
Treatment
Revision fixation with graft
Malunion
Incidence
Variable
Prevention
Fluoroscopic reduction checks
Treatment
Corrective osteotomy if symptomatic
Infection
Incidence
Low (small incisions)
Prevention
Aseptic technique, antibiotics
Treatment
Debridement, antibiotics, retain or remove hardware
Hardware irritation
Incidence
Variable
Prevention
Bury screws, low-profile plate
Treatment
Hardware removal after union
Post-operative complications
ComplicationIncidencePreventionTreatment
Iatrogenic radial nerve palsyLow with correct techniqueBrachialis protection, stay on boneObservation, EMG, explore if persistent
NonunionLowBiological bridge plating, stable constructRevision fixation with graft
MalunionVariableFluoroscopic reduction checksCorrective osteotomy if symptomatic
InfectionLow (small incisions)Aseptic technique, antibioticsDebridement, antibiotics, retain or remove hardware
Hardware irritationVariableBury screws, low-profile plateHardware removal after union

Post-operative care and outcomes. Perform a neurovascular check documenting wrist and finger extension against the pre-operative baseline; a sling or splint is used for comfort, with early gentle pendulum and elbow movement as the construct is usually stable. Progress to active-assisted shoulder and elbow range of movement, then strengthening once callus appears, with typical union at three to four months. Follow up at two weeks (wound check and suture removal), six weeks (radiographs, assess callus, advance movement), twelve weeks (radiographs, confirm progression to union, progress loading) and six months (clinical and radiographic review of union). MIPO aims to preserve biology so the construct fails by callus rather than hardware; compared with open plating it reports lower infection and comparable union, and compared with intramedullary nailing it avoids shoulder entry-point problems but demands greater reliance on fluoroscopy and indirect reduction.

Procedures Through This Approach


Bridge plating of a humeral shaft fracture
Suitability
Primary indication
Notes
Long plate, low screw density, indirect reduction
Pathological or impending fracture fixation
Suitability
Excellent
Notes
Long plate spans lesional bone; cement augmentation optional
Segmental shaft fracture fixation
Suitability
Excellent
Notes
One construct spans multiple zones
Paediatric or adolescent shaft fracture (selected)
Suitability
Good
Notes
Smaller plates; respect the physes
Delayed union or nonunion with biologics
Suitability
Selected
Notes
Preserve biology; add graft through the windows
Intra-articular fracture reduction
Suitability
Not suitable
Notes
Requires a formal open articular approach
Procedures performed through the anterior MIPO corridor
ProcedureSuitabilityNotes
Bridge plating of a humeral shaft fracturePrimary indicationLong plate, low screw density, indirect reduction
Pathological or impending fracture fixationExcellentLong plate spans lesional bone; cement augmentation optional
Segmental shaft fracture fixationExcellentOne construct spans multiple zones
Paediatric or adolescent shaft fracture (selected)GoodSmaller plates; respect the physes
Delayed union or nonunion with biologicsSelectedPreserve biology; add graft through the windows
Intra-articular fracture reductionNot suitableRequires a formal open articular approach

Viva & Exam Focus


At a glance. The anterior MIPO corridor delivers a long, biology-preserving bridge plate through two small windows β€” a proximal deltopectoral window (deltoid, axillary nerve, versus pectoralis major, pectoral nerves) and a distal anterolateral window between biceps (musculocutaneous nerve) and brachialis β€” joined by a submuscular, extrasynovial, epiperiosteal tunnel on the anterior cortex. The patient is positioned supine on a radiolucent table with the whole humerus visible to fluoroscopy. The brachialis is the key protective structure: splitting it in its mid-substance and leaving the lateral half intact interposes muscle between the plate and the radial nerve, which pierces the lateral intermuscular septum roughly 10 cm proximal to the lateral epicondyle. Reduction is indirect β€” length, alignment and rotation are restored under image intensification with traction, percutaneous clamps, blocking screws and the plate itself as a template, while the fracture haematoma is left undisturbed.

Mnemonic

ANTERIORANTERIOR β€” the corridor in eight steps

A
Arm supine
Supine on a radiolucent table
N
No fracture exposure
Preserve biology; haematoma untouched
T
Two windows
Deltopectoral and anterolateral
E
Epiperiosteal tunnel
Submuscular, strictly on bone
R
Radial nerve
Protected by the brachialis
I
Indirect reduction
Fluoroscopic; length, alignment, rotation
O
One long plate
Bridge construct, low screw density
R
Range of movement
Early, once stable
Mnemonic

DANGERDANGER β€” structures at risk by layer

D
Deltoid split
Endangers the axillary nerve proximally
A
Anterior circumflex artery
Encountered in the proximal window
N
Nerve at risk distally
The radial nerve β€” most feared
G
Groove (deltopectoral)
Protect the cephalic vein
E
Errors of plane
Expose the musculocutaneous nerve medially
R
Reduce under fluoroscopy
Avoids malunion
Mnemonic

BRIDGEBRIDGE β€” construct principles

B
Biology preserved
Fracture haematoma untouched
R
Restoration
Of length, alignment and rotation, indirectly
I
Indirect reduction
With clamps and blocking screws
D
Distant windows
Away from the fracture
G
Gap tolerated
Elastic bridging supports callus
E
Elastic long plate
With low screw density

Clinical Decision Scenarios

Practise clinical reasoning and management decisions out loud

Viva scenarioStandard
Clinical prompt

β€œA 34-year-old cyclist sustains a comminuted closed mid-shaft humeral fracture with acceptable alignment. You favour surgical fixation with a minimally invasive bridge plate. Describe your approach.”

Viva scenarioChallenging
Clinical prompt

β€œOn the morning after MIPO plating of a humeral shaft fracture, the patient cannot extend the wrist or fingers. How do you assess and manage this?”

Viva scenarioStandard
Clinical prompt

β€œHow do you decide the balance between the proximal and distal windows for an anterior MIPO humeral plate, and how can the approach be extended?”

Exam day cheat sheet
MIPO anterior humeral corridor β€” exam-day essentials

Position

  • Supine on a radiolucent table
  • Ipsilateral scapula boosted; arm free on an armboard or across the chest
  • Confirm full AP and lateral fluoroscopy of the entire humerus before draping
  • Pad all pressure points; tourniquet only if it does not obstruct imaging

Two windows

  • Proximal: deltopectoral interval (or anterolateral deltoid split)
  • Distal: anterolateral between biceps and brachialis
  • Both incisions remote from the fracture β€” biology preserved
  • Submuscular extrasynovial tunnel joins them on the anterior cortex

Internervous planes

  • Proximal: deltoid (axillary) versus pectoralis major (pectoral nerves)
  • Distal superficial: biceps (musculocutaneous) retracted medially
  • Distal deep: split the brachialis (dual innervation β€” safe)
  • Lateral half of brachialis left intact to protect the radial nerve

Structures at risk

  • Radial nerve β€” most feared; protected by the lateral brachialis cuff
  • Radial nerve pierces the lateral intermuscular septum about 10 cm above the lateral epicondyle
  • Axillary nerve at risk proximally with a distal deltoid split
  • Musculocutaneous and lateral antebrachial cutaneous nerves at risk medially
  • Cephalic vein in the deltopectoral groove

Reduction and fixation

  • Indirect reduction: restore length, alignment and rotation
  • Traction, percutaneous clamps, blocking screws, plate as template
  • Long bridge plate with low screw density (elastic construct)
  • At least three bicortical screws proximal and distal, spread along the plate

Closure and pitfalls

  • No deep closure β€” muscle falls back over the plate
  • Close fascia, subcutaneous tissue and skin in layers
  • Early gentle shoulder and elbow movement once stable
  • Watch for radial nerve palsy β€” document pre- and post-operative function

References


Guidelines, registries and global practice. Humeral shaft fractures are managed worldwide, and operative decision-making converges across examination systems. The majority of closed shaft fractures can be managed non-operatively with functional bracing; operative fixation is reserved for unacceptable alignment, open fractures, polytrauma, bilateral injuries, vascular compromise and pathology. MIPO bridge plating is a recognised biological option alongside intramedullary nailing and open plating. Side-by-side principles (where guidance converges):

AO Foundation
Position on humeral shaft fixation
Biological plating with long plates, low screw density and indirect reduction; respect the soft tissues; bridge comminution rather than compress it
BOA / BOAST
Position on humeral shaft fixation
Early soft-tissue assessment; definitive fixation once conditions permit; documented neurovascular status including radial nerve function
AAOS / OTA
Position on humeral shaft fixation
Operative fixation for open fractures, polytrauma, vascular injury, unacceptable alignment and pathological fractures; restore length, alignment and rotation
Guidance convergence for humeral shaft fixation
BodyPosition on humeral shaft fixation
AO FoundationBiological plating with long plates, low screw density and indirect reduction; respect the soft tissues; bridge comminution rather than compress it
BOA / BOASTEarly soft-tissue assessment; definitive fixation once conditions permit; documented neurovascular status including radial nerve function
AAOS / OTAOperative fixation for open fractures, polytrauma, vascular injury, unacceptable alignment and pathological fractures; restore length, alignment and rotation

Registry and population evidence: - Humeral shaft fractures represent a small fraction of long-bone fractures, with an incidence of roughly 13 to 15 per 100,000 per year and a bimodal distribution (high-energy in young adults, low-energy falls in older patients).

  • Functional bracing remains the benchmark non-operative comparator, with high union rates reported in large cohorts; operative series for MIPO and nailing report broadly comparable union with technique-specific complications. Global practice variation. In high-resource settings, pre-contoured locking anterior humeral plates and full intra-operative fluoroscopy are standard. In resource-limited settings, the same biological principles are achieved with standard large-fragment plates contoured intra-operatively, and functional bracing retains a larger role. Consent (globally applicable): discuss iatrogenic radial nerve palsy (the principal neurological risk), infection (low with small incisions), nonunion and malunion, hardware irritation, and the possibility of revision surgery.
For the operative surgery station

Describe the anterior MIPO corridor systematically: supine positioning and fluoroscopy, the proximal deltopectoral and distal anterolateral windows, the brachialis split that protects the radial nerve, the submuscular tunnel, indirect reduction, and the principles of biological bridge plating.

Evidence

Minimally Invasive Plate Osteosynthesis (MIPO) of the Humeral Shaft Fracture: Is It Possible?

LoE 4
Apivatthakakul T, Arpornchayanon O, Bavornratanavech S β€’ Injury (2005)
Key Findings:
  • Cadaveric and preliminary clinical study establishing that a long plate can be delivered to the anterior humeral shaft through proximal and distal windows without exposing the fracture
  • Demonstrated that the brachialis can be split to create the distal part of the tunnel while keeping a lateral muscular cuff over the radial nerve
  • Showed the feasibility of the two-incision anterior MIPO technique and its biological rationale
  • Formed the technical foundation for subsequent clinical MIPO series of humeral shaft fractures
Evidence

Guidelines for the Clinical Application of the LCP

LoE 5
Gautier E, Sommer C β€’ Injury (2003)
Key Findings:
  • Defined the principles of locked plating including bridge plating for comminuted fractures
  • Recommended long plates with widely spaced screws to create flexible, biology-preserving constructs
  • Emphasised low screw density to distribute strain and avoid stress concentration
  • Provided the conceptual basis for the long bridge plate construct used in MIPO
Evidence

Fractures of the Humerus with Radial-Nerve Paralysis

LoE 4
Holstein A, Lewis GB β€’ Journal of Bone and Joint Surgery (Am) (1963)
Key Findings:
  • Described the distal-third oblique and spiral humeral shaft fracture pattern associated with radial nerve injury
  • Showed that the radial nerve is tethered where it pierces the lateral intermuscular septum, making it vulnerable at this level
  • Established the anatomical rationale for why the distal third is the danger zone for the radial nerve
  • Remains the eponymous reference for understanding radial nerve risk in humeral shaft fractures
Evidence

Functional Bracing of Fractures of the Shaft of the Humerus

LoE 4
Sarmiento A, Kinman PB, Galvin EG, Latta LL, Ziliolia JE β€’ Journal of Bone and Joint Surgery (Am) (1977)
Key Findings:
  • Landmark report establishing functional bracing as the non-operative standard for closed humeral shaft fractures
  • Reported high union rates with bracing across a large cohort of shaft fractures
  • Defined acceptable alignment parameters that guide the decision to operate or to continue non-operative care
  • Provides the benchmark against which operative methods including MIPO are compared
Editorially reviewed β€” transparent references and correction processPublished by OrthoVellum Medical Education TeamEditorial boardMethodologyReview policy
Educational disclosure

Educational content is reviewed for source visibility, editorial coherence, and correction readiness.

No individual clinician credential is claimed unless a named person is shown.

Verify before clinical use; this is not medical advice or a substitute for local guidance.

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Peer-reviewed Β· 2026-06-20
Procedure info
Level
advanced
Read time
24 min
Updated
2026-06-20
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