Knee arthrodesis is a salvage surgery that permanently fuses (locks) your knee joint in a straight or near-straight position, creating a solid bone connection between femur (thigh bone) and tibia (shin bone), eliminating knee motion but providing pain-free, stable weight-bearing. This major procedure is reserved for situations where knee replacement is not possible or has failed multiple times—typically after severe infection requiring implant removal, multiple failed knee replacements with poor bone stock, or young patients with destroyed knees unsuitable for replacement. While it eliminates knee pain (90-95% success), it creates permanent disability requiring compensatory hip/ankle motion and assistive devices, making it a last-resort option when the alternative is amputation or permanent non-weight-bearing.