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Evidence. Clarity. Practice.

© 2026 OrthoVellum. For educational purposes only.

Not medical advice. Verify clinically important information against current local guidance.

Back to Research
Level VMust KnowBasic ScienceExpert Opinion

Evidence brief

AO Principles

AO Principles of Fracture Management

Authors
Müller ME, Allgöwer M, Schneider R, Willenegger H
Journal
Manual of Internal Fixation
Year
1969

Key Findings

  • 1

    Anatomic reduction (especially articular)

  • 2

    Stable internal fixation

  • 3

    Preservation of blood supply

  • 4

    Early, safe mobilization

  • 5

    Evolved to include biological fixation

Clinical Implications

AO principles revolutionized fracture care by providing a systematic approach to internal fixation. Modern adaptation emphasizes biology alongside mechanics.

Teaching Note

Original 4 principles evolved with biological understanding. Modern emphasis: anatomic articular reduction, relative stability acceptable for metaphyseal/diaphyseal. Know lag screw principle, plate functions (compression, neutralization, buttress, bridge). Understand locking vs conventional screws.

Citation

Müller ME, Allgöwer M, Schneider R, Willenegger H. Manual of Internal Fixation: Techniques Recommended by the AO-ASIF Group. Berlin: Springer; 1969.

Evidence Level

V

Level V

Expert opinion or mechanism-based reasoning

Topics

AOfracture fixationprinciplesinternal fixation

Related Topics

  • Fracture Fixation
  • Plate Osteosynthesis
  • Biomechanics

External Links

Related Papers

V

Perren Strain Theory

Perren SM (1979)

V

Wolff's Law

Wolff J (1892)

V

Tissue Viscoelasticity

Fung YC (1993)

V

Orthopaedic Biomaterials

Ratner BD (2004)