Cervical Disc Arthroplasty (Total Disc Replacement)

SpineAdvancedCore Procedure

Cervical Disc Arthroplasty (Total Disc Replacement)

Operative technique guide for cervical total disc arthroplasty as a motion-preserving alternative to ACDF for single- or two-level cervical radiculopathy or myelopathy from soft-disc herniation

High-yield overview

Motion-preserving cervical total disc replacement via Smith-Robinson anterior approach | advanced

Surgical Imaging

Critical Danger Structures and Exam Traps
Recurrent Laryngeal Nerve β€” Right vs Left Approach

The trap: Assuming a right-sided approach is always safer or that nerve injury risk is symmetric.

The fix: The recurrent laryngeal nerve loops under the subclavian on the right and under the aortic arch on the left. At C6-7 the right nerve is more vulnerable because its course is more oblique and superficial. Most surgeons therefore select a left-sided Smith-Robinson approach for C6-7 arthroplasty. Document the side chosen and the rationale in the operative note.

Sympathetic Chain and Horner Syndrome

Location: The sympathetic chain lies on the longus colli muscle approximately 10-15 mm lateral to the midline; aggressive lateral retraction or electrocautery can cause permanent Horner syndrome.

Risk: Unilateral ptosis, miosis and anhidrosis. Prevention requires staying strictly within the medial half of the longus colli when releasing the prevertebral fascia and avoiding monopolar cautery near the lateral border.

Oesophagus and Pharynx β€” Retraction Injury

Location: The oesophagus lies immediately medial to the carotid sheath and is retracted with a blunt blade or self-retaining retractor with smooth blades.

Risk: Perforation presents with post-operative neck swelling, crepitus, fever and dysphagia. Prevention includes gentle blunt dissection, frequent relaxation of retractors, and placement of a nasogastric tube in high-risk revisions to allow palpation of the oesophageal wall.

Vertebral Artery β€” Lateral Foramen Violation

Location: The vertebral artery enters the transverse foramen at C6 and ascends within the uncinate process region; the distance from midline to artery at C5-6 is approximately 15-18 mm.

Risk: Aggressive lateral decompression or uncinate resection can lacerate the artery, causing massive bleeding or posterior circulation stroke. Always confirm the position of the uncovertebral joints on pre-operative CT and limit lateral resection to the medial half of the uncinate.

Endplate Over-Preparation and Subsidence

Why different: Excessive removal of subchondral bone or use of an oversized implant leads to early subsidence and loss of segmental lordosis.

Implications: Ideal preparation removes only cartilage while preserving dense endplate bone. Intra-operative fluoroscopy must confirm that the implant footprint covers at least 80 percent of the endplate and that distraction is limited to 2 mm above resting disc height.

Heterotopic Ossification versus Persistent Motion Loss

Recognition: Bridging bone anterior or posterior to the implant on lateral radiographs at 6-24 months indicates Grade III-IV heterotopic ossification and loss of the motion-preserving benefit.

Prevention: Meticulous haemostasis, avoidance of bone dust in the field, and consideration of short-course NSAID prophylaxis in high-risk patients (male sex, multilevel disease). Once formed, revision to fusion is the only reliable salvage.

Mnemonic

S.M.I.T.HAPPROACH β€” Smith-Robinson Anterior Cervical Exposure

Mnemonic

I.M.P.L.A.N.TIMPLANT β€” Critical Technical Points for Cervical TDR

Mnemonic

C.O.M.P.L.E.XCOMPLICATION β€” Recognition and Prevention of TDR Failures

Surgical Indications

Absolute Indications

  • Single- or two-level cervical radiculopathy or myelopathy from soft-disc herniation with preserved segmental motion
  • Failure of at least 6 weeks of non-operative management including physiotherapy, NSAIDs and selective nerve root blocks
  • Patient preference for motion preservation after informed discussion of adjacent-segment disease risk

Relative Indications

  • Young active patient (less than 60 years) with minimal facet arthrosis and no significant kyphosis or instability
  • Two-level disease where fusion would create a long lever arm and increase stress on adjacent segments
  • Professional or recreational need for preserved cervical rotation and flexion-extension

Contraindications

Absolute:

  • Ankylosis or spontaneous fusion at the index level
  • Severe spondylosis with greater than 50 percent disc height loss or large posterior osteophytes
  • Osteoporosis (T-score less than -2.5) or metabolic bone disease
  • Active infection, tumour or inflammatory arthropathy
  • Greater than 2 mm translation on dynamic radiographs (instability)
  • Significant cervical kyphosis (greater than 10 degrees segmental)

Relative:

  • Previous anterior cervical surgery at the same level
  • Severe facet arthropathy or arthropathy requiring posterior decompression
  • Multilevel disease (three or more levels) β€” higher risk of heterotopic ossification and motion loss
  • Smoking or systemic steroids that impair bone ingrowth

Evidence Base

Motion Preservation versus Fusion

Cervical disc arthroplasty was developed to reduce the incidence of adjacent-segment degeneration that occurs in 25-30 percent of patients at 10 years after ACDF. By preserving physiologic motion, the theoretical load transfer to adjacent discs and facets is reduced.

Landmark Randomised Controlled Trials

Multiple FDA IDE trials (Prestige, ProDisc-C, Secure-C, PCM, Mobi-C) demonstrated non-inferiority to ACDF at 2 and 7 years with superior preservation of range of motion and lower re-operation rates for adjacent-segment disease in some series.

Heterotopic Ossification

The most common device-specific complication. Incidence ranges from 10-50 percent at 5 years depending on implant design and patient factors. Grade III-IV HO eliminates the motion-preserving benefit and converts the arthroplasty into a de facto fusion.

Adjacent-Segment Disease

Meta-analyses suggest a modest reduction in symptomatic adjacent-segment disease requiring surgery (approximately 50 percent relative risk reduction at 7-10 years) but the absolute benefit remains small and long-term data beyond 10 years are still maturing.


Clinical Decision Scenarios

Practise clinical reasoning and management decisions out loud

Viva scenarioAdvanced
Clinical prompt

β€œA 48-year-old man with single-level C5-6 soft-disc herniation causing radiculopathy has failed 8 weeks of conservative treatment. Dynamic radiographs show 8 degrees of motion at C5-6, no instability, and CT confirms minimal facet arthrosis. He is keen to avoid fusion. Outline your indications assessment and operative plan for cervical disc arthroplasty.”

Practical approach
This patient meets the classic indications for cervical total disc arthroplasty: single-level soft-disc pathology, preserved motion greater than 5 degrees, minimal facet disease, no instability or kyphosis, and failure of non-operative care. **Pre-operative assessment**: I would obtain MRI to confirm the soft-disc herniation and rule out significant cord signal change, CT to assess endplate morphology and uncovertebral joints, and dynamic radiographs to quantify motion and exclude instability. I would discuss the theoretical reduction in adjacent-segment disease risk versus the risk of heterotopic ossification and the possibility that motion may be lost over time. **Operative plan**: Left-sided Smith-Robinson approach at C5-6 (level confirmed by fluoroscopy). Standard exposure between carotid sheath and visceral column. Complete discectomy including posterior annulus and any compressive uncovertebral osteophytes. Endplate preparation preserving subchondral bone. Midline placement of an appropriately sized implant confirmed on AP and lateral fluoroscopy. Intra-operative confirmation of full nerve-root decompression. Layered closure without drain. Immediate mobilisation without collar. **Post-operative care**: Early range-of-motion exercises from week 2, dynamic radiographs at 6 weeks and 3 months to confirm motion preservation, and surveillance for heterotopic ossification at annual review.
Viva scenarioAdvanced
Clinical prompt

β€œYou are planning a C6-7 cervical disc arthroplasty. The patient is a 52-year-old woman with C7 radiculopathy. Describe the specific anatomic considerations at C6-7 and how they influence your approach and implant placement.”

Practical approach
C6-7 is the most common level for arthroplasty but carries unique anatomic risks that must be addressed. **Recurrent laryngeal nerve anatomy**: At C6-7 the right recurrent laryngeal nerve has a more oblique and superficial course. I therefore select a left-sided Smith-Robinson approach at this level to minimise hoarseness risk. I document the rationale in the operative note. **Oesophageal retraction**: The oesophagus is widest at C6-7 and lies immediately medial to the carotid sheath. I place a nasogastric tube pre-operatively to allow palpation during medial retraction and I relax the retractors every 15-20 minutes to reduce ischaemic injury. **Vertebral artery position**: The artery enters the C6 transverse foramen. Lateral decompression must stay within the medial half of the uncinate process. Pre-operative CT confirms the distance from midline to the foramen (typically 15-18 mm at C6-7). **Implant considerations**: The C6-7 disc space is often narrower and more lordotic than C5-6. I select an implant with appropriate lordotic angle (usually 6-8 degrees) and confirm that the footprint covers at least 80 percent of the endplate on the AP view. Over-sizing risks endplate fracture in the narrower C7 body. **Intra-operative fluoroscopy**: The shoulders are taped caudally and the C-arm is positioned to obtain clear AP and lateral views of C6-7 before skin incision.
Viva scenarioAdvanced
Clinical prompt

β€œA 45-year-old man undergoes uneventful single-level C5-6 arthroplasty. On the first post-operative day he develops progressive neck swelling, dysphagia and stridor. What is your differential diagnosis and immediate management?”

Practical approach
This presentation suggests an expanding prevertebral haematoma with airway compromise β€” a surgical emergency. **Immediate actions**: Call for airway and ENT support. Do not wait for imaging. Transfer to theatre for immediate wound exploration and evacuation of haematoma. Intubate early if stridor worsens; have a difficult-airway plan ready. **Differential diagnosis**: (1) Post-operative haematoma from inadequate haemostasis or arterial bleeding, (2) Oesophageal perforation with mediastinitis (less likely without fever or crepitus initially), (3) Seroma or CSF collection (unlikely to cause rapid airway compromise). **Intra-operative findings and management**: Re-open the wound through the original incision. Evacuate the haematoma. Identify and control any active bleeding (usually from longus colli or epidural veins). Inspect the oesophagus for perforation (rare). Leave a drain and close in layers. Post-operative ICU monitoring for airway swelling. Broad-spectrum antibiotics if oesophageal injury is suspected. **Prevention in future cases**: Meticulous bipolar haemostasis before closure, consider a drain in patients with large raw surfaces, and maintain a low threshold for re-exploration in any patient with progressive neck swelling.
Exam day cheat sheet
Cervical Disc Arthroplasty β€” Exam Day Summary

References

Evidence

Long-term Clinical Outcomes of Cervical Disc Arthroplasty: A Prospective, Randomized, Controlled Trial

Level I
Sasso WR, Smucker JD, Sasso MP, Sasso RC β€’ Spine (Phila Pa 1976)
Clinical implication: Cervical disc arthroplasty provides durable clinical outcomes and motion preservation beyond 5 years in appropriately selected patients.
Source: Spine (Phila Pa 1976) 2017;42(4):209-216
Evidence

Cervical disc arthroplasty with the Prestige LP disc versus anterior cervical discectomy and fusion, at 2 levels: results of a prospective, multicenter randomized controlled clinical trial at 24 months

Level I
Gornet MF, Lanman TH, Burkus JK, Hodges SD, McConnell JR, Dryer RF, Copay AG, Nian H, Harrell FE Jr β€’ J Neurosurg Spine
Clinical implication: Two-level cervical disc arthroplasty is a safe and effective motion-preserving alternative to fusion with reduced adjacent-segment stress.
Source: J Neurosurg Spine 2017;26(6):653-667
Evidence

Cervical Disk Arthroplasty and Range of Motion at 7 Years: Impact on Adjacent Level Degeneration

Level I
Satin AM, Rogers-LaVanne MP, Derman PB β€’ Clin Spine Surg
Clinical implication: Preserved motion at 7 years correlates with lower rates of adjacent segment degeneration, supporting long-term benefit of arthroplasty.
Source: Clin Spine Surg 2023;36(3):83-89
Evidence

Ten-year Outcomes of Cervical Disc Replacement With the BRYAN Cervical Disc: Results From a Prospective, Randomized, Controlled Clinical Trial

Level I
Lavelle WF, Riew KD, Levi AD, Florman JE β€’ Spine (Phila Pa 1976)
Clinical implication: Long-term (10-year) evidence confirms durability of motion preservation and reduced re-operation risk with cervical disc arthroplasty.
Source: Spine (Phila Pa 1976) 2019;44(9):601-608
Editorially reviewed β€” transparent references and correction processPublished by OrthoVellum Medical Education TeamEditorial boardMethodologyReview policy
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