Spine

Cervical Spinal Fusion (ACDF)

Comprehensive surgical technique guide for Anterior Cervical Discectomy and Fusion (ACDF) - evidence-based approach for cervical degenerative disease

Core Procedure
intermediate
By OrthoVellum Medical Education Team

Reviewed by OrthoVellum Editorial Team

Editorial maintenance, source checking, and correction workflow • Published by OrthoVellum Medical Education Team

High Yield Overview

ANTERIOR CERVICAL DISCECTOMY & FUSION (ACDF)

Gold standard surgical approach for cervical degenerative disease with neural compression - Smith-Robinson technique with contemporary instrumentation | intermediate

Five Critical Anatomical Danger Zones

Recurrent Laryngeal Nerve

Location: Travels in tracheoesophageal groove - RIGHT side more vulnerable (loops under subclavian at T1-2, ascends obliquely). LEFT side loops predictably under aortic arch.

Protection: Left-sided approach preferred. Avoid retractor placement in tracheoesophageal groove. Endotracheal tube pressure monitoring - deflate/reposition q30min. Intraoperative neuromonitoring if revision/multilevel surgery.

Superior Laryngeal Nerve

Location: Exits vagus at C3 level, travels deep to carotid to pierce thyrohyoid membrane. At risk with high approaches (C3-4, C2-3) or excessive superior retraction.

Protection: Dissect only to level of surgical exposure required. Gentle superior retraction with handheld Cloward retractors. Avoid monopolar diathermy near carotid sheath above C4.

Vertebral Artery

Location: Enters transverse foramen C6 (90%) or C5 (8%). Courses 3mm lateral to uncovertebral joint. Anomalous course in 5% (medial deviation).

Protection: Limit lateral dissection to medial border of uncinate process. Preoperative CTA if revision surgery or dysplastic anatomy. Angled curettes directed medially only. Uncovertebral drilling with 3mm diamond burr at 45° trajectory.

Spinal Cord

Location: Average AP diameter cervical canal 14mm (range 10-20mm). Cord occupies 12mm - CSF 1mm anterior. Stenotic canal means minimal safety margin with instruments.

Protection: Decompress lateral-to-medial sequence. Kerrison rongeurs bite away from cord (upbiting). Trial spacer before final implant - oversizing risks cord compression. Intraoperative SSEPs/MEPs for stenotic canals or ossification of PLL.

Esophagus

Location: Immediately medial to dissection plane. Thin wall (3mm) highly vulnerable to retractor pressure, diathermy thermal injury, or sharp dissection.

Protection: Handheld retraction initially until NG tube palpated. Smooth blade retractors (not teeth). Retract esophagus gently medially - limit pressure (60-80mmHg max). Irrigate frequently. Bipolar only near midline. Methylene blue swallow test if concern.

Mnemonic

POETSACDF Approach Layers - 'POETS'

Mnemonic

DUBSACDF Decompression Sequence - 'DUBS'

Primary Indications

Absolute Indications

  • Progressive cervical myelopathy with cord compression (modified JOA score decline)
  • Cervical radiculopathy failing 6-12 weeks conservative management with MRI-confirmed nerve root compression
  • Cervical kyphotic deformity with anterior column deficiency requiring reconstruction
  • Post-traumatic cervical instability (facet disruption, ALL/disc injury) requiring stabilization
  • Anterior cervical tumor/infection requiring corpectomy and reconstruction

Relative Indications

  • Cervical radiculopathy with concordant imaging and high-demand occupation
  • Multilevel cervical spondylosis with predominant axial neck pain (controversial - consider arthroplasty)
  • Soft disc herniation with persistent radicular symptoms despite optimized non-operative care
  • Adjacent segment disease following prior cervical fusion

Contraindications

  • Absolute: Active systemic infection, severe osteoporosis (DEXA T-score less than -3.5), medical instability
  • Relative: Multilevel disease (greater than 3 levels - consider hybrid constructs), smoker (2.7x pseudarthrosis risk), significant dysphagia baseline, ankylosing spondylitis (avoid through fused segments)

Preoperative Planning Essentials

Imaging Analysis

  • MRI: T2 signal changes in cord (myelomalacia poor prognosis), disc hydration, foraminal stenosis grade
  • CT: Assess ossification of PLL (40% Asian population), uncovertebral hypertrophy, facet arthropathy
  • Flexion-extension radiographs: Document instability (greater than 3mm translation or greater than 11° angulation)
  • CTA: If revision surgery (scar tissue distorts anatomy) or vascular anomaly suspected

Patient Optimization

  • Smoking cessation 8 weeks minimum (proven 3x fusion rate improvement)
  • Diabetic HbA1c less than 7.5% (wound healing, infection risk reduction)
  • BMI optimization - obesity associated with higher dysphagia, revision rates
  • Discontinue NSAIDs 1 week preoperatively (theoretical fusion concern)

Graft and Instrumentation Selection

  • Autograft iliac crest: Gold standard fusion (98% single-level) but donor site pain 20%
  • Allograft structural: Equivalent fusion with anterior plating (95% vs 98%), no donor morbidity
  • PEEK cage with demineralized bone matrix: Contemporary standard - subsidence risk 5-8%
  • Anterior cervical plate: Reduces pseudarthrosis 3-level from 44% to 8%, angular kyphosis
  • Zero-profile devices: Standalone cage with integrated screws - lower dysphagia (12% vs 28% at 3 months)

Postoperative Care Protocol

Immediate Postoperative (0-24 hours)

  • Monitor airway closely in PACU - risk of hematoma, edema, RLN palsy (keep anesthesia available)
  • Soft cervical collar for comfort (not structural - fusion relies on graft/plate, not collar)
  • Head of bed elevated 30° (reduce venous pressure, swelling)
  • Ice packs to anterior neck (reduce edema)
  • Diet: Clear liquids advance to soft diet as tolerated (dysphagia common 70% at 1 week)
  • Remove drain (if placed) when output less than 30mL per 8 hours (typically POD1)

Early Recovery (1-6 weeks)

  • Mobilize immediately - no bed rest required
  • Collar weaned over 2 weeks (comfort only, not necessary for fusion)
  • Avoid heavy lifting (greater than 10 pounds), contact sports, extreme neck movements (extension/rotation)
  • Radiographs at 2 weeks (AP, lateral) - assess alignment, hardware position
  • Sutures removed 10-14 days (if non-absorbable used)
  • Return to desk work 2-4 weeks, manual labor 6-12 weeks

Late Recovery (6 weeks to 1 year)

  • Flexion-extension radiographs at 3 months (assess early fusion)
  • CT scan at 6-12 months if concern for pseudarthrosis (persistent pain, no bridging bone on radiographs)
  • Physical therapy if neck stiffness, periscapular pain (common 40%)
  • Fusion confirmed radiographically: Bridging bone across graft, less than 2mm motion on flexion-extension, less than 5° angular change

VTE Prophylaxis

  • Low risk surgery (1-2 hours, minimal blood loss) - early mobilization sufficient
  • High-risk patients (obesity BMI greater than 35, prior VTE, cancer, prolonged surgery greater than 3 hours) - sequential compression devices, LMWH (enoxaparin 40mg daily) starting POD1 (avoid preoperative dosing - hematoma risk)

Pain Management

  • Multimodal analgesia: Paracetamol 1g QID, gabapentin 300mg TID (radicular pain)
  • Opioids as needed (oxycodone 5-10mg q4-6h) - minimize duration (risk dependency)
  • Avoid NSAIDs first 3 months (theoretical concern for fusion - controversial, weak evidence)
  • Ice therapy, gentle ROM exercises

Exam Viva Scenarios

Practice these scenarios to excel in your viva examination

VIVA SCENARIOStandard

EXAMINER

"A 52-year-old lawyer presents with 8 months of right arm pain radiating to the thumb and index finger, with numbness. MRI shows a right C6-7 paracentral disc herniation compressing the C7 nerve root. He has failed 3 months of physiotherapy and anti-inflammatories. How would you manage this patient and what are the key operative steps if you proceed with ACDF?"

EXCEPTIONAL ANSWER
This patient has clinical and radiological evidence of C6-7 radiculopathy from disc herniation with failed conservative management - he is a candidate for surgical decompression. ACDF is the gold standard surgical treatment with 90% excellent/good outcomes for radiculopathy. I would explain the risks (recurrent laryngeal nerve injury 1-2% left-sided approach, dysphagia 30% early improving to 10% at 1 year, infection less than 1%, catastrophic complications like cord injury or vertebral artery injury less than 0.5%), benefits (pain relief 90%, return to work 80%), and alternatives (posterior foraminotomy - motion preservation but higher recurrence, observation with ongoing symptoms). Key operative steps include: (1) Positioning supine with shoulder roll, left-sided approach, (2) Transverse skin incision at C6-7 level (2 fingerbreadths above suprasternal notch), (3) Blunt dissection between carotid sheath and visceral column, (4) Self-retaining retractor placement under longus colli bilaterally, (5) Localization radiograph confirming C6-7 level, (6) Anterior discectomy removing nucleus and cartilaginous endplates to bleeding bone, (7) Posterior decompression with Kerrison rongeurs resecting posterior osteophytes and lateral disc herniation compressing C7 root - foraminotomy to decompress nerve completely, (8) Endplate preparation parallel surfaces, (9) Interbody graft placement (PEEK cage with local bone or allograft) restoring disc height and lordosis, (10) Anterior cervical plate fixation with 4 screws for stability, (11) Final fluoroscopy confirming position, (12) Hemostasis and layered closure. Postoperatively collar for comfort, early mobilization, flexion-extension radiographs at 3 months to confirm fusion.
VIVA SCENARIOStandard

EXAMINER

"During ACDF at C5-6, after anterior discectomy you are performing posterior decompression with a Kerrison rongeur when you encounter brisk arterial bleeding from the left lateral disc space. What has happened, what are your immediate steps, and how do you prevent this complication?"

EXCEPTIONAL ANSWER
This is a vertebral artery injury - a catastrophic but rare complication (0.3-0.5% of ACDF cases). The vertebral artery ascends through the transverse foramina of C6 to C1, passing 3mm lateral to the uncovertebral joint. Injury typically occurs during lateral decompression (uncovertebral osteophyte removal) or overly aggressive lateral discectomy beyond the safe zone. Immediate management: (1) Remain calm and alert the team, (2) Apply direct pressure with cottonoid patties, (3) Continue pressure for 5-10 minutes allowing assistant to call vascular surgery urgently, (4) If bleeding continues, pack with hemostatic agents (Gelfoam soaked in thrombin, Surgicel, bone wax pressed into foramen), (5) Avoid blind bipolar coagulation (risks thrombosis and posterior circulation stroke), (6) Do NOT attempt to clip or ligate (this causes stroke), (7) Maintain adequate MAP greater than 80mmHg to ensure contralateral vertebral perfusion, (8) Once hemostasis achieved, complete the decompression and fusion as planned on contralateral side only, (9) Obtain postoperative angiography (CT angiogram or conventional) to assess vessel patency and pseudoaneurysm formation, (10) Neurology consultation, monitor for posterior circulation stroke symptoms (ataxia, diplopia, dysphagia), (11) If pseudoaneurysm identified, interventional radiology may perform coil embolization or stenting. Prevention strategies include: (1) Limit lateral dissection to medial border of uncinate process (never extend lateral to longus colli attachment), (2) Preoperative CTA if revision surgery or congenital anomaly suspected, (3) Use angled curettes directed medially (not laterally) during discectomy, (4) Perform uncovertebral osteophyte drilling with 3mm diamond burr at 45° medial trajectory under direct vision, (5) Stay in midline during posterior decompression with Kerrison, (6) Copious irrigation during drilling to clear bone dust and visualize anatomy. Most vertebral artery injuries are venous plexus injuries (managed with pressure/packing), but true arterial injury requires multidisciplinary management and may result in stroke despite optimal treatment.
VIVA SCENARIOStandard

EXAMINER

"You are planning ACDF for a 45-year-old manual laborer with C5-6 and C6-7 disc herniations causing bilateral arm pain. What are your graft options and how would you counsel the patient regarding fusion rates, complications, and expected functional outcomes for two-level ACDF?"

EXCEPTIONAL ANSWER
For two-level ACDF (C5-6, C6-7), I would counsel regarding three main graft options: (1) Autograft iliac crest - gold standard with highest fusion rates (98%) but 20% donor site pain, increased operative time 20-30 minutes, risk of lateral femoral cutaneous nerve injury 5%, graft fracture or hematoma 2%; (2) Structural allograft (cadaveric bone) - equivalent fusion to autograft when combined with anterior plating (92-95%), no donor site morbidity, slightly higher subsidence risk (8-12%), uses bone bank tissue (theoretical infection/disease transmission risk though extremely low with modern screening); (3) PEEK interbody cage (polyetheretherketone) packed with morselized local bone or demineralized bone matrix - fusion rates 92-95%, radiolucent allowing better postoperative imaging, subsidence risk 5-8%, lower profile may reduce dysphagia. For two-level fusion, I would recommend structural allograft or PEEK cages with anterior cervical plating - this combination provides 90-95% fusion rates while avoiding iliac crest donor morbidity. Anterior plate is mandatory for two-level surgery (reduces pseudarthrosis from 18% to 8% and prevents kyphosis). Expected outcomes: (1) Symptom relief excellent/good in 85-90%, with bilateral radiculopathy expect 80% relief arm pain, 70% return to manual labor by 6 months; (2) Fusion rates 90-95% at 1 year (confirmed on CT or flexion-extension radiographs); (3) Complications - dysphagia 40-50% at 1 month improving to 15-20% at 1 year (higher than single-level), recurrent laryngeal nerve palsy 2-3%, pseudarthrosis 8-10% with plating, adjacent segment disease 2.9% per year (same as single-level); (4) Return to work: Desk work 4-6 weeks, manual labor 3-4 months, restrict heavy lifting (greater than 25 pounds) until fusion confirmed (6-12 months); (5) Alternative of cervical disc arthroplasty not appropriate for two-level disease (FDA approval only for single-level, outcomes data limited for multilevel arthroplasty). I would also discuss smoking cessation (2.7x higher pseudarthrosis risk), optimization of diabetes, bone health (DEXA if postmenopausal female or risk factors for osteoporosis), and realistic expectations that two-level fusion results in approximately 50% reduction in cervical ROM but functional impact minimal for most activities of daily living.

ACDF - Exam Day Essentials

High-Yield Exam Summary

References

  1. Smith GW, Robinson RA. The treatment of certain cervical-spine disorders by anterior removal of the intervertebral disc and interbody fusion. J Bone Joint Surg Am. 1958;40-A(3):607-624. Original description of anterior cervical approach and interbody fusion technique - established ACDF as gold standard treatment for cervical disc disease.

  2. Bohlman HH, Emery SE, Goodfellow DB, Jones PK. Robinson anterior cervical discectomy and arthrodesis for cervical radiculopathy. Long-term follow-up of one hundred and twenty-two patients. J Bone Joint Surg Am. 1993;75(9):1298-1307. Demonstrated 92% fusion rate with autograft and anterior plating versus 67% without plating for multilevel ACDF - established role of anterior instrumentation.

  3. Hilibrand AS, Carlson GD, Palumbo MA, Jones PK, Bohlman HH. Radiculopathy and myelopathy at segments adjacent to the site of a previous anterior cervical arthrodesis. J Bone Joint Surg Am. 1999;81(4):519-528. Defined adjacent segment disease - 2.9% annual incidence, 25% cumulative at 10 years post-ACDF, established importance of maintaining cervical lordosis.

  4. Wang JC, McDonough PW, Endow KK, Delamarter RB. Increased fusion rates with cervical plating for two-level anterior cervical discectomy and fusion. Spine. 2000;25(1):41-45. Meta-analysis showing fusion rates: autograft 93%, allograft 88%, anterior plating improves both to 96-98% - evidence base for routine plating in multilevel surgery.

  5. Riley LH 3rd, Skolasky RL, Albert TJ, Vaccaro AR, Heller JG. Dysphagia after anterior cervical decompression and fusion: prevalence and risk factors from a longitudinal cohort study. Spine. 2005;30(22):2564-2569. Demonstrated dysphagia incidence 50-60% at 1 month, 12-14% at 12 months, identified multilevel surgery and prominent hardware as risk factors - established importance of low-profile implants.

  6. Fountas KN, Kapsalaki EZ, Nikolakakos LG, et al. Anterior cervical discectomy and fusion associated complications. Spine. 2007;32(21):2310-2317. Comprehensive complication analysis: RLN palsy 1-8%, vertebral artery injury 0.3-0.5%, postoperative hematoma 0.5-2%, esophageal injury 0.1-0.25% - established complication benchmarks for quality improvement.

  7. Yue WM, Brodner W, Highland TR. Long-term results after anterior cervical discectomy and fusion with allograft and plating: a 5- to 11-year radiologic and clinical follow-up study. Spine. 2005;30(19):2138-2144. Demonstrated equivalent fusion rates allograft with plating (95%) versus autograft (98%) with no donor site morbidity - shifted practice toward allograft as contemporary standard.

  8. Basques BA, Anandasivam NS, Webb ML, et al. Risk factors for blood transfusion with primary posterior lumbar fusion. Spine. 2015;40(18):1792-1797. Identified obesity, multilevel surgery, operative time greater than 3 hours as transfusion risk factors - informs preoperative optimization and blood conservation strategies.

  9. Shin DA, Yi S, Yoon DH, Kim KN, Shin HC. Artificial disc replacement combined with fusion versus two-level fusion in cervical two-level disc disease. Spine. 2014;39(15):1233-1239. Hybrid constructs (arthroplasty + fusion) for two-level disease showed superior ROM preservation and similar clinical outcomes versus two-level ACDF - emerging alternative to consider.

  10. Australian Orthopaedic Association National Joint Replacement Registry. Hip, Knee & Shoulder Arthroplasty: 2023 Annual Report. Adelaide: AOA; 2023. Australian registry data showing 15,000 ACDF procedures annually, infection rate 0.8%, reoperation 3.2% at 2 years - benchmark outcomes for Australian practice.