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Evidence. Clarity. Practice.

© 2026 OrthoVellum. For educational purposes only.

Not medical advice. Verify clinically important information against current local guidance.

Back to Research
Level IVHigh YieldBasic ScienceBasic Science

Evidence brief

Tendon Healing Biology

Tendon Healing and Repair Biology

Authors
Sharma P, Maffulli N
Journal
J Bone Joint Surg Am
Year
2005

Key Findings

  • 1

    Intrinsic healing from tendon cells

  • 2

    Extrinsic healing from surrounding tissues

  • 3

    Inflammatory, proliferative, remodeling phases

  • 4

    Scar tissue weaker than native tendon

  • 5

    Motion affects healing quality

Clinical Implications

Understanding tendon healing biology guides surgical technique and postoperative rehabilitation. Early controlled motion improves healing quality.

Teaching Note

Know the phases: inflammatory (0-7 days), proliferative (7-21 days), remodeling (3 weeks to 1 year). Intrinsic vs extrinsic healing. Tendinopathy: failed healing response, not inflammation. Early motion prevents adhesions, improves strength. Balance repair strength vs motion.

Citation

Sharma P, Maffulli N. Tendon injury and tendinopathy: healing and repair. J Bone Joint Surg Am. 2005;87(1):187-202.

PubMed

Evidence Level

IV

Level IV

Case series or case reports

Topics

tendon healingtendinopathyrepair biology

Related Topics

  • Tendon Repair
  • Tendinopathy
  • Rehabilitation

External Links

View on PubMed

Related Papers

IV

Bone Graft Biology

Khan SN (2005)

V

Perren Strain Theory

Perren SM (1979)

V

AO Principles

Müller ME (1969)

V

Wolff's Law

Wolff J (1892)