Skip to main content
OrthoVellumOrthopaedic Exam Prep
Pricing
About OrthoVellum
OrthoVellum
A living orthopaedic atlas

Exam-focused orthopaedic references, a question bank, viva practice, and spaced-repetition revision — with every clinical claim traceable to its source. Content is educational only and is not a substitute for local supervision, clinical judgement, or institutional policy.


Library

  • Clinical Topics
  • Blog
  • Site Updates
  • Content Methodology

Company

  • About Us
  • Authors & Disclosure
  • Editorial Team
  • Editorial Policy
  • Advertising Policy

Legal

  • Terms of Service
  • Privacy Policy
  • Cookie Policy
  • Medical Disclaimer
  • Copyright & DMCA

Support

  • Support OrthoVellum
  • Help Center
  • Contact
  • Accessibility
Evidence. Clarity. Practice.

© 2026 OrthoVellum. For educational purposes only.

Not medical advice. Verify clinically important information against current local guidance.

Back to Research
Level IIMust KnowSports MedicineProspective Cohort

Evidence brief

MOON:MOON ACL Cohort

Multicenter Orthopaedic Outcomes Network (MOON) ACL Reconstruction Cohort

Authors
MOON Knee Group, Spindler KP, Huston LJ, et al
Journal
Am J Sports Med
Year
2011

Key Findings

  • 1

    Largest prospective ACL reconstruction cohort (3,000+ patients)

  • 2

    Risk factors for poor outcome: smoking, low education, high BMI

  • 3

    Meniscal and cartilage status affects outcomes

  • 4

    Return to sport rates vary by graft type and sport

  • 5

    10-year data shows 7-10% revision rate

Clinical Implications

MOON cohort provides high-quality outcome data for ACL reconstruction. Results inform patient counseling about expected outcomes and risk factors for failure.

Teaching Note

Reference MOON data when discussing ACL reconstruction outcomes. Know risk factors for poor outcome. Compare graft choices and their outcomes. Discuss patient factors that influence counseling.

Citation

Spindler KP et al. Predictors of poor 2-year outcome after ACL reconstruction (MOON cohort). Am J Sports Med. 2011;39(12):2536-2541.

PubMedDOI

Evidence Level

II

Level II

Lesser quality RCT or prospective comparative study

Topics

ACLreconstructionoutcomesprospective cohortMOON

Related Topics

  • Acl Reconstruction
  • Acl Graft Selection
  • Knee Ligament Injuries

External Links

View on PubMedView via DOI

Related Papers

II

MARS Revision ACL Study

MARS Group (2014)

II

Return to Sport Criteria

Grindem H (2016)

III

Meniscal Repair Outcomes

Stein T (2010)

III

Rotator Cuff Repair Evidence

Galatz LM (2004)